Šukele Renāte, Lauberte Liga, Kovalcuka Liga, Logviss Konstantins, Bārzdiņa Ance, Brangule Agnese, Horváth Zoltán Márk, Bandere Dace
Department of Pharmaceutical Chemistry, Riga Stradiņš University, LV-1007 Riga, Latvia.
Department of Pharmaceuticals, Red Cross Medical College of Riga Stradiņš University, LV-1009 Riga, Latvia.
Plants (Basel). 2023 May 12;12(10):1968. doi: 10.3390/plants12101968.
The L. (Tansy) has several ethnobotanical uses, mostly related to the essential oil and sesquiterpene lactones, whereas information regarding other compounds is scarce. This research is designed to characterize the phenolic compounds (flavonoids, phenolic acids, and tannins) to analyze the thujone (which is toxic in high concentrations) content and to detect the antioxidant activity (DPPH assay) of extracts. The main highlights of our work provide a chemical profile of phenolic compounds of harvested from different regions of Latvia, as well as simultaneously support the ethnomedicinal uses for wild through the integration of phenolic compounds as one of the value constituents of leaves and flowers. The extraction yield was 18 to 20% for leaves and 8 to 16% for flowers. The total phenol content in the extracts of as well as their antioxidant activity was different between collection regions and the aerial parts ranging from 134 to 218 mg GAE/g and 32 to 182 mg L, respectively. A remarkable variation in the thujone (α + β) content (0.4% up to 6%) was detected in the extracts. leaf extracts were rich in tannins (up to 19%). According to the parameters detected, the extracts of could be considered promising for the development of new herbal products.
艾菊(Tanacetum vulgare L.)有多种民族植物学用途,大多与精油和倍半萜内酯有关,而关于其他化合物的信息则很少。本研究旨在对酚类化合物(黄酮类、酚酸类和单宁类)进行表征,分析侧柏酮(高浓度时有毒)含量,并检测提取物的抗氧化活性(DPPH 法)。我们工作的主要亮点在于提供了从拉脱维亚不同地区采集的艾菊酚类化合物的化学概况,同时通过将酚类化合物作为叶和花的重要成分之一,支持了艾菊在民族医学中的用途。叶的提取率为 18%至 20%,花的提取率为 8%至 16%。不同采集地区和地上部分的艾菊提取物中总酚含量及其抗氧化活性有所不同,分别在 134 至 218 毫克没食子酸当量/克和 32 至 182 毫克 Trolox 当量/克之间。提取物中侧柏酮(α + β)含量存在显著差异(0.4%至 6%)。艾菊叶提取物富含单宁(高达 19%)。根据检测参数,艾菊提取物有望用于开发新的草药产品。