Suppr超能文献

南非桑寄生提取物的植物化学筛选、抗氧化及抗菌特性

Phytochemical Screening, Antioxidant and Antibacterial Properties of Extracts of , a South African Mistletoe.

作者信息

Mapfumari Sipho, Nogbou Noel-David, Musyoki Andrew, Gololo Stanley, Mothibe Mmamosheledi, Bassey Kokoette

机构信息

Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, P.O. Box 218, Pretoria 0208, South Africa.

Department of Microbiology, School of Medicine, Sefako Makgatho Health Sciences University, P.O Box 211, Pretoria 0208, South Africa.

出版信息

Plants (Basel). 2022 Aug 12;11(16):2094. doi: 10.3390/plants11162094.

Abstract

is a woody evergreen semi-parasitic shrub that grows on the branches of other trees. It is used by African traditional healers for post-stroke management. This study reports on the qualitative phytochemical screening and the antioxidant and antimicrobial activities of acetone, methanol, hexane and dichloromethane extracts. Standard protocols for the phytochemical screening of extracts were employed. TLC bio-autography was used for qualitative antioxidants analysis. Assays: 2,2-diphenyl-1-picrylhydrazyl, HO free-radical scavenging and ferric chloride reducing power were carried out for quantitative antioxidant analysis. The antimicrobial potential of extracts was screened using disc diffusion, bio-autography and broth micro-dilution. The results indicate the presence of alkaloids, phenolics and tannins in all extracts. Acetone and methanol revealed significant amount of saponins, phenolics, tannins and terpenoids. The extracts exhibited significant antioxidant potential on TLC with positive compound bands at an Rf range of 0.05-0.89. DPPH, HO and the reduction of Fe to Fe assays indicated that methanol extract has a strong antioxidant potential, followed by acetone, DCM and lastly hexane. The extracts of show the potential to be antibacterial agents. It can be concluded that extracts contain phytochemicals which are capable of mitigating against chronic health conditions such as cancer, stroke and stress-related and infectious diseases.

摘要

是一种木质常绿半寄生灌木,生长在其他树木的枝条上。非洲传统治疗师用它来进行中风后的治疗。本研究报告了丙酮、甲醇、己烷和二氯甲烷提取物的定性植物化学筛选以及抗氧化和抗菌活性。采用了提取物植物化学筛选的标准方案。薄层色谱生物自显影用于定性抗氧化剂分析。进行了2,2-二苯基-1-苦基肼、羟基自由基清除和氯化铁还原能力测定以进行定量抗氧化剂分析。使用纸片扩散法、生物自显影法和肉汤微量稀释法筛选提取物的抗菌潜力。结果表明所有提取物中均存在生物碱、酚类和单宁。丙酮和甲醇显示出大量的皂苷、酚类、单宁和萜类化合物。提取物在薄层色谱上表现出显著的抗氧化潜力,在Rf范围为0.05 - 0.89时有阳性化合物条带。二苯基苦味酰基自由基(DPPH)、羟基自由基(HO)以及铁离子还原测定表明甲醇提取物具有很强的抗氧化潜力,其次是丙酮、二氯甲烷,最后是己烷。提取物显示出具有抗菌剂的潜力。可以得出结论,提取物含有能够缓解慢性健康状况如癌症、中风以及与压力相关的疾病和传染病的植物化学物质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbb9/9412615/c0e9b3c6f604/plants-11-02094-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验