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悉尼西部地区与东部和北部地区在中风治疗可及性方面存在显著差异。

Significant Disparity of Access to Stroke Treatment Between the Western Parts and Eastern and Northern Parts of Sydney.

作者信息

Eftekhar Behzad

机构信息

Neurological Surgery, University of Sydney, Sydney, AUS.

Neurological Surgery, Macquarie University, Sydney, AUS.

出版信息

Cureus. 2023 Aug 28;15(8):e44285. doi: 10.7759/cureus.44285. eCollection 2023 Aug.

DOI:10.7759/cureus.44285
PMID:37654903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10467637/
Abstract

Objective To provide an estimate of access times and distances to an endovascular clot retrieval (ECR) service provider for a typical stroke patient in the western part of Sydney and to compare it with the eastern and northern parts. Methods Incidences of stroke were simulated through a population-weighted randomized selection of addresses in the studied western, eastern, and northern areas of Sydney (100,000 times for each). The access times and distances were calculated from those addresses to the closest ECR hub for the eastern and northern parts and to all five ECR hubs, as well as the Nepean Public Hospital (NPH) for the western part. The access times and distance means were compared statistically using ANOVA. Results In the western areas, the estimated average access times and distances to different ECR hubs varied from 38.5 (+/- 15) to 45 (+/- 15) minutes and from 42 (+/- 15.9) to 46.8 (+/- 16) km in working hours and from 45 (+/- 15) to 64 (+/- 15) minutes and 46.8 (+/- 16) to 69.6 (+/- 16) km in after hours. However, the estimated average access times and distances to the local ECR hub were 12.25 (+/- 6) minutes and 9.1 (+/- 5.6) km for northern and 7.5 (+/- 4) minutes and 4.4 (+/- 2.5) km for the eastern areas. The differences between the estimated average access times and distances for a typical stroke patient to an ECR hub in the western areas in comparison with eastern or northern areas were statistically significant (p<0.0001). The average access times and distances in the western part to NPH were 17 (+/- 16) minutes and 15.6 (+/- 16.6) km. Conclusions The patients in the western part of Sydney had significantly longer access times to ECR hubs than those living in comparable areas of the eastern and northern parts. This study supports the Nepean Public Hospital supplying an ECR service to achieve travel times, and, therefore, treatment times for a typical stroke patient in the western parts, similar to patients in the eastern and northern parts of Sydney.

摘要

目的 评估悉尼西部典型中风患者前往血管内血栓清除(ECR)服务机构的就诊时间和距离,并与悉尼东部和北部进行比较。方法 通过对悉尼西部、东部和北部研究区域的地址进行人口加权随机选择来模拟中风发病率(每个区域100,000次)。计算从这些地址到东部和北部最近的ECR中心、西部所有五个ECR中心以及内佩恩公立医院(NPH)的就诊时间和距离。使用方差分析对就诊时间和距离均值进行统计学比较。结果 在西部地区,工作日前往不同ECR中心的估计平均就诊时间和距离分别为38.5(±15)至45(±15)分钟和42(±15.9)至46.8(±16)千米,非工作时间分别为45(±15)至64(±15)分钟和46.8(±16)至69.6(±16)千米。然而,北部地区前往当地ECR中心的估计平均就诊时间和距离分别为12.25(±6)分钟和9.1(±5.6)千米,东部地区为7.5(±4)分钟和4.4(±2.5)千米。与东部或北部地区相比,悉尼西部典型中风患者前往ECR中心的估计平均就诊时间和距离差异具有统计学意义(p<0.0001)。西部地区前往NPH的平均就诊时间和距离分别为17(±16)分钟和15.6(±16.6)千米。结论 悉尼西部地区的患者前往ECR中心的就诊时间明显长于悉尼东部和北部类似地区的患者。本研究支持内佩恩公立医院提供ECR服务,以使悉尼西部地区典型中风患者的出行时间以及治疗时间与悉尼东部和北部地区患者相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/10467637/09701c217da5/cureus-0015-00000044285-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/10467637/09701c217da5/cureus-0015-00000044285-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/10467637/09701c217da5/cureus-0015-00000044285-i01.jpg

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本文引用的文献

1
Healthy Life-Year Costs of Treatment Speed From Arrival to Endovascular Thrombectomy in Patients With Ischemic Stroke: A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials.健康生命年治疗速度成本:来自 7 项随机临床试验的个体患者数据的荟萃分析。 **解析**: - Healthy Life-Year(健康生命年):这是一个医学术语,用于衡量一个人在健康状态下的生存时间。 - Treatment Speed(治疗速度):指的是从到达医院到开始接受血管内血栓切除术的时间。 - Ischemic Stroke(缺血性中风):一种由于脑血管阻塞导致的脑部缺血性疾病。 - Meta-analysis(荟萃分析):一种统计学方法,用于综合和分析多个研究的结果。 - Individual Patient Data(个体患者数据):指的是每个患者的详细医疗记录和数据。 - Randomized Clinical Trial(随机临床试验):一种医学研究方法,用于评估新的治疗方法的效果。
JAMA Neurol. 2021 Jun 1;78(6):709-717. doi: 10.1001/jamaneurol.2021.1055.
2
Googling Service Boundaries for Endovascular Clot Retrieval (ECR) Hub Hospitals in Metropolitan Sydney.搜索悉尼大都市地区血管内血栓清除术(ECR)中心医院的服务范围
Front Neurol. 2019 Jul 2;10:708. doi: 10.3389/fneur.2019.00708. eCollection 2019.
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Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging.6至16小时卒中的血栓切除术及灌注成像选择
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Googling Service Boundaries for Endovascular Clot Retrieval Hub Hospitals in a Metropolitan Setting: Proof-of-Concept Study.在大都市环境中搜索血管内血栓清除中心医院的服务边界:概念验证研究。
Stroke. 2017 May;48(5):1353-1361. doi: 10.1161/STROKEAHA.116.015323. Epub 2017 Mar 29.
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Editorial: Time is brain!社论:时间就是大脑!
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Thrombectomy within 8 hours after symptom onset in ischemic stroke.发病 8 小时内进行缺血性脑卒中取栓治疗。
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N Engl J Med. 2015 Mar 12;372(11):1019-30. doi: 10.1056/NEJMoa1414905. Epub 2015 Feb 11.
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Endovascular therapy for ischemic stroke with perfusion-imaging selection.血管内治疗缺血性卒中的灌注成像选择。
N Engl J Med. 2015 Mar 12;372(11):1009-18. doi: 10.1056/NEJMoa1414792. Epub 2015 Feb 11.
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N Engl J Med. 2015 Jan 1;372(1):11-20. doi: 10.1056/NEJMoa1411587. Epub 2014 Dec 17.
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