Karpov L M, Rozanov A Ia, Filippova T O
Vopr Med Khim. 1986 Jul-Aug;32(4):136-9.
Equimolar doses (30 mM/kg) of 35S-labelled thiamin, thiamin monophosphate or benzoyl thiamin monophosphate were administered intraperitoneally into mice. Increase in content of labelled metabolites, derived from 35S-benzoyl thiamin monophosphate, as compared with 35S-thiamin and 35S-thiamin monophosphate, was more distinct and prolonged in mice tissues, especially in brain and heart muscle, within 6-24 hrs. In blood this relationship was opposite. Total 35S was excreted with urine also at the highest rate after the 35S-benzoyl thiamin monophosphate administration as compared with the effect of thiamin and thiamin monophosphate but differences between the experimental data obtained with the latter compounds were only slight.
将等摩尔剂量（30 mM/kg）的35S标记硫胺素、硫胺素单磷酸酯或苯甲酰硫胺素单磷酸酯腹腔注射到小鼠体内。与35S-硫胺素和35S-硫胺素单磷酸酯相比，源自35S-苯甲酰硫胺素单磷酸酯的标记代谢物在小鼠组织中的含量增加在6至24小时内更为明显且持续时间更长，尤其是在脑和心肌中。在血液中，这种关系则相反。与硫胺素和硫胺素单磷酸酯的作用相比，注射35S-苯甲酰硫胺素单磷酸酯后，总35S也以最高速率随尿液排出，但后两种化合物获得的实验数据之间的差异仅很小。
