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[我们关于心肌梗死二级预防的研究结果]

[Our results with the secondary prevention of myocardial infarct].

作者信息

Popova B, Karalambev N

出版信息

Vutr Boles. 1986;25(4):50-4.

PMID:3765590
Abstract

The communication summed up the results from the two prospective follow-up care-prophylactic studies on patients with a past history of acute myocardial infarction (AMI). The first study covers all patients, with a past history of AMI and discharged in 1963, 1964, 1966 and 1967, a total of 378, with a follow-up period from 6 to 11 years. The direct task of the follow up was the prevention of a repeated infarction. The prophylactic measures, carried out with the followed-up patients were: control of body mass by a hypocaloric and antisclerotic diet, sufficient physical activity and medicamentous treatment when needed. Two groups of patients were differentiated: experimental (the patients adhering to the instructions prescribed) an control (patients that did not adhere to the recommendations for correction of body mass with no motor regimen). After the termination of the observation it was established that 12.6% from the experimental group had repeated infarction and 28.3%--in the control group. The lethality in the experimental group was 21.7% and in the control--43.9%. The second prospective observation covered 250 patients (reduced to 241 in time), with a past history of AMI and discharged within the year 1975. The follow up lasted for 5 years under the same conditions of follow-up care. Summing up our 5-year secondary prophylaxis carried out mainly with a diet, physical activity and partially with antiaggregants and medicamentous treatment when needed, we could ascertain and draw the conclusions.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

该通讯总结了两项针对有急性心肌梗死(AMI)病史患者的前瞻性后续护理 - 预防研究的结果。第一项研究涵盖了所有在1963年、1964年、1966年和1967年出院的有AMI病史的患者,共计378例,随访期为6至11年。随访的直接任务是预防再次梗死。对随访患者采取的预防措施包括:通过低热量和抗硬化饮食控制体重、进行足够的体育活动以及在需要时进行药物治疗。区分了两组患者:实验组(遵守规定医嘱的患者)和对照组(未遵守体重纠正建议且无运动方案的患者)。观察结束后发现,实验组中有12.6%的患者再次梗死,对照组中这一比例为28.3%。实验组的死亡率为21.7%,对照组为43.9%。第二项前瞻性观察涵盖了250例(随访期间减少至241例)有AMI病史且于1975年内出院的患者。在相同的随访护理条件下随访持续了5年。总结我们主要通过饮食、体育活动以及在需要时部分使用抗血小板药物和药物治疗进行的5年二级预防,我们可以确定并得出结论。(摘要截短为250字)

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