State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China; Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China; Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China; National Basic Science Data Center, Beijing, China.
J Am Acad Child Adolesc Psychiatry. 2024 Jan;63(1):25-28. doi: 10.1016/j.jaac.2023.08.006. Epub 2023 Aug 30.
The connectome, generally defined as a comprehensive map of the structural and/or functional connections of a complete set of neural elements, has been recognized to condense the mechanistic architecture of the brain and capture meaningful individual differences. Increasing efforts are being invested in exploring the associations between connectomes and behavior/symptoms to piece together guidelines from a systems/cognitive neuroscience perspective for reforming mental health care. This editorial sketches a road to mental health with lifespan connectome gradients (LCG), highlighting unique perspectives, prospects, and priorities.
连接组学通常被定义为完整的神经单元的结构和/或功能连接的综合图谱,它被认为可以浓缩大脑的机械结构,并捕捉到有意义的个体差异。越来越多的人致力于探索连接组学与行为/症状之间的联系,以便从系统/认知神经科学的角度拼凑出改革精神卫生保健的指导方针。本社论勾勒了一条带有寿命连接组梯度 (LCG) 的精神健康之路,突出了独特的观点、前景和优先事项。