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添加执行功能训练于暴食障碍的认知行为治疗中:一项先导随机对照试验。

Adding executive function training to cognitive behavioral therapy for binge eating disorder: A pilot randomized controlled trial.

机构信息

University of California San Diego, Department of Pediatrics, 9500 Gilman Drive, La Jolla, CA 92093, USA.

University of California San Diego, Herbert Wertheim School of Public Health and Human Longevity Science, 9500 Gilman Drive, La Jolla, CA 92093, USA.

出版信息

Eat Behav. 2023 Dec;51:101806. doi: 10.1016/j.eatbeh.2023.101806. Epub 2023 Aug 29.

Abstract

Evidence-based treatments for binge eating disorder (BED), such as cognitive behavioral therapy (CBT) lead to successful outcomes only about half the time. Individuals with BED often have measurable deficits in executive function (EF) that may challenge adherence to or impact of cognitive behavioral intervention components. The aim of this study was to evaluate the impact of adding EF training to CBT by combining CBT with a compensatory cognitive training approach (EF-CBT). Participants were 32 adults with BED, overweight/obesity, and comorbid anxiety or depression who were randomly assigned to four months of group treatment in either standard CBT or EF-CBT. Outcomes were assessed at baseline, post-treatment, and at 2-month follow-up. Results showed that EF-CBT was feasible and acceptable, comparable to CBT. Both groups significantly decreased loss of control (LOC) days, clinical impairment, and depression at post-treatment and 2-month follow-up; though there were no differences between groups. Neither group significantly reduced anxiety or weight. Exploratory analyses found that participants with lower EF treated with EF-CBT were less likely to have LOC at post-treatment than those with lower EF treated with CBT. Higher self-monitoring rates during treatment were associated with lower LOC at post-treatment and participants with lower EF were more likely to self-monitor in the EF-CBT arm relative to the CBT arm. These findings suggest that EF-CBT is feasible, acceptable and efficacious, although larger scale research is needed. EF-CBT may be particularly suited for individuals with BED who have lower EF.

摘要

针对暴食症(BED)的循证治疗方法,如认知行为疗法(CBT),只有大约一半的时间能取得成功。BED 患者的执行功能(EF)通常存在可衡量的缺陷,这可能会影响对认知行为干预措施的坚持或影响。本研究的目的是通过将 CBT 与补偿性认知训练方法(EF-CBT)相结合,评估在 CBT 中加入 EF 训练对治疗的影响。参与者是 32 名患有 BED、超重/肥胖且伴有焦虑或抑郁共病的成年人,他们被随机分配到为期四个月的标准 CBT 或 EF-CBT 小组治疗中。在基线、治疗后和 2 个月随访时评估结果。结果表明,EF-CBT 是可行且可接受的,与 CBT 相当。两组患者在治疗后和 2 个月随访时均显著减少了失控(LOC)天数、临床损伤和抑郁;但两组之间没有差异。两组均未显著降低焦虑或体重。探索性分析发现,接受 EF-CBT 治疗的 EF 较低的患者在治疗后 LOC 较少,而接受 CBT 治疗的 EF 较低的患者则较少。治疗期间更高的自我监测率与治疗后 LOC 较低有关,EF 较低的患者在 EF-CBT 组比 CBT 组更有可能进行自我监测。这些发现表明,EF-CBT 是可行的、可接受的和有效的,尽管需要更大规模的研究。EF-CBT 可能特别适合 EF 较低的 BED 患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abd7/10840715/5abb8abd1e3a/nihms-1929180-f0001.jpg

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