Division of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School. 110 Francis St, Suite 3B. Boston, MA 02215, USA.
Department of Surgery, Massachusetts General Hospital, Harvard Medical School. 165 Cambridge St, Boston, MA 02114, USA.
Spine J. 2023 Dec;23(12):1830-1837. doi: 10.1016/j.spinee.2023.08.018. Epub 2023 Sep 1.
Anterior cervical discectomy and fusion (ACDF) is a commonly-performed and generally well-tolerated procedure used to treat cervical disc herniation. Rarely, patients require discharge to inpatient rehab, leading to inconvenience for the patient and increased healthcare expenditure for the medical system.
The objective of this study was to create an accurate and practical predictive model for, as well as delineate associated factors with, rehab discharge following elective ACDF.
This was a retrospective, single-center, cohort study.
Patients who underwent ACDF between 2012 and 2022 were included. Those with confounding diagnoses or who underwent concurrent, staged, or nonelective procedures were excluded.
Primary outcomes for this study included measurements of accuracy for predicting rehab discharge. Secondary outcomes included associations of variables with rehab discharge.
Current Procedural Terminology codes identified patients. Charts were reviewed to obtain additional demographic and clinical characteristics on which an initial univariate analysis was performed. Two logistic regression and two machine learning models were trained and evaluated on the data using cross-validation. A multimodel logistic regression was implemented to analyze independent variable associations with rehab discharge.
A total of 466 patients were included in the study. The logistic regression model with minimum corrected Akaike information criterion score performed best overall, with the highest values for area under the receiver operating characteristic curve (0.83), Youden's J statistic (0.71), balanced accuracy (85.7%), sensitivity (90.3%), and positive predictive value (38.5%). Rehab discharge was associated with a modified frailty index of 2 (p=.007), lack of home support (p=.002), and having Medicare or Medicaid insurance (p=.007) after correction for multiple hypotheses.
Nonmedical social determinants of health, such as having public insurance or a lack of support at home, may play a role in rehab discharge following elective ACDF. In combination with the modified frailty index and other variables, these factors can be used to predict rehab discharge with high accuracy, improving the patient experience and reducing healthcare costs.
颈椎前路椎间盘切除融合术(ACDF)是一种常见且耐受性良好的手术,用于治疗颈椎间盘突出症。但极少数患者需要出院到住院康复中心,这给患者带来不便,并增加了医疗系统的医疗支出。
本研究旨在创建一个准确且实用的预测模型,以确定颈椎前路椎间盘切除融合术后患者接受康复治疗的出院概率,并探讨与康复治疗出院相关的因素。
这是一项回顾性、单中心、队列研究。
纳入 2012 年至 2022 年间接受 ACDF 的患者。排除伴有混淆诊断或接受同期、分期或非选择性手术的患者。
本研究的主要结局是评估预测康复治疗出院的准确性。次要结局包括变量与康复治疗出院的关联。
使用当前操作术语代码识别患者。查阅图表以获取更多人口统计学和临床特征的附加信息,并对其进行单变量分析。使用交叉验证在数据上训练和评估了两种逻辑回归和两种机器学习模型。实施多模型逻辑回归分析以分析与康复治疗出院相关的独立变量。
共有 466 名患者纳入研究。具有最小校正赤池信息量准则评分的逻辑回归模型总体表现最佳,其接受者操作特征曲线下面积最高(0.83)、约登指数(0.71)、平衡准确性(85.7%)、敏感性(90.3%)和阳性预测值(38.5%)最高。经多假设校正后,康复治疗出院与改良衰弱指数 2(p=.007)、缺乏家庭支持(p=.002)和拥有医疗保险或医疗补助(p=.007)相关。
非医疗社会健康决定因素,如拥有公共保险或家庭支持不足,可能在颈椎前路椎间盘切除融合术后的康复治疗出院中发挥作用。与改良衰弱指数和其他变量相结合,这些因素可用于高度准确地预测康复治疗出院,改善患者体验并降低医疗成本。