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美甲师和美甲材料消费者中甲基丙烯酸甲酯致敏的预后和后遗症。

Prognosis and sequelae of meth(acrylate) sensitization in beauticians and consumers of manicure materials.

机构信息

Dermatology Department, Hospital Universitario de Toledo, Toledo, Spain.

Escuela Internacional de Doctorado, Universidad de Castilla-La-Mancha, Toledo, Spain.

出版信息

Contact Dermatitis. 2023 Dec;89(6):471-479. doi: 10.1111/cod.14408. Epub 2023 Sep 4.

Abstract

BACKGROUND

Allergic contact dermatitis from (meth)acrylic monomers (ACDMA) in manicure products is increasing.

OBJECTIVE

To evaluate the prognosis, work performance impairment and sequelae of a cohort of beauticians and manicure consumers with ACDMA sensitized from the exposure to manicure products.

METHODS

We conducted a telephone survey with patients diagnosed with ACDMA.

RESULTS

One hundred and six patients were evaluated, including 75 (70.8%) beauticians and 31 (29.2%) consumers. All were women with a mean age of 39 (19-62). Thirty-seven of 75 beauticians (49.3%) continued to work. Twenty-seven of 106 (25.5%) patients continued to use manicure products with (meth)acrylates regularly. Seventeen of 51 (33.3%) patients who discontinued the exposure described ongoing nail/periungual changes. Nine of 58 (15.5%) patients who required dental restoration, orthodontic or occlusal splint materials recalled reactions from them; and, 25 of 96 (26%) who used sanitary napkins recalled intolerance to them starting after the diagnosis of ACDMA. Fifteen of 25 (60%) discontinued the use of sanitary napkins.

CONCLUSION

49.3% beauticians continued to work; most patients stopped wearing acrylic manicure materials; reactions from dental materials were not uncommon, however, removal of dental materials was never required; and, reactions to sanitary napkins developing after the diagnosis of ACDMA were common most leading to discontinuation of use.

摘要

背景

美甲产品中的(甲基)丙烯酸单体引起的接触性过敏皮炎(ACDMA)正在增加。

目的

评估一组因接触美甲产品而对美甲产品中的(甲基)丙烯酸单体产生过敏反应的美容师和美甲消费者的预后、工作表现受损和后遗症。

方法

我们对诊断为 ACDMA 的患者进行了电话调查。

结果

共评估了 106 名患者,包括 75 名(70.8%)美容师和 31 名(29.2%)消费者。所有患者均为女性,平均年龄为 39 岁(19-62 岁)。75 名美容师中有 37 名(49.3%)继续工作。106 名患者中有 27 名(25.5%)继续定期使用含(甲基)丙烯酸酯的美甲产品。51 名停止暴露的患者中有 17 名(33.3%)描述指甲/甲周仍有持续变化。96 名需要牙修复、正畸或咬合夹板材料的患者中有 9 名(15.5%)回忆起对这些材料有过敏反应;96 名使用卫生巾的患者中有 25 名(26%)回忆起在诊断出 ACDMA 后对它们不耐受;其中 15 名(60%)停止使用卫生巾。

结论

49.3%的美容师继续工作;大多数患者停止使用丙烯酸指甲材料;牙材料的反应并不少见,但从未需要去除牙材料;诊断出 ACDMA 后出现的卫生巾过敏反应很常见,大多数患者因此停止使用。

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