Magni G, Di Mario F, Rizzardo R, Pulin S, Naccarato R
Am J Psychiatry. 1986 Oct;143(10):1297-300. doi: 10.1176/ajp.143.10.1297.
Cluster analysis of personality profiles determined by the Sixteen Personality Factor Questionnaire separated 79 patients with duodenal ulcer into three homogeneous subgroups: 32 dependent and anxious patients, 31 neurotic and anxious patients, and 16 patients with a balanced personality. No significant differences among these three groups emerged for the variables of age, sex, duration of illness, fasting total serum pepsinogen, fasting serum pepsinogen group I, and number of cigarettes smoked per day, although there was a nonsignificant trend for both pepsinogen values to be higher in the patients with a balanced personality than in the other two groups. These results support the concept of heterogeneity of peptic ulcer disease.
通过十六种人格因素问卷确定的人格特征聚类分析，将79例十二指肠溃疡患者分为三个同质亚组：32例依赖且焦虑的患者、31例神经质且焦虑的患者以及16例人格平衡的患者。在年龄、性别、病程、空腹血清总胃蛋白酶原、空腹血清胃蛋白酶原I组以及每日吸烟数量这些变量上，这三组之间未出现显著差异，尽管人格平衡的患者中胃蛋白酶原值均有高于其他两组的非显著趋势。这些结果支持消化性溃疡病异质性的概念。
