Li Yong-Zhen, Wu Xiao-Chuan
Department of Pediatrics, Second Xiangya Hospital, Central South University, Changsha 410000, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2023 Aug 15;25(8):785-790. doi: 10.7499/j.issn.1008-8830.2302150.
Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organ systems, presenting a complex and diverse clinical manifestation. The heterogeneous treatment response and prognosis of SLE pose significant challenges to its diagnosis, classification, and homogeneous treatment. The emergence of new technologies and fields, such as synthetic biology, genomics, and proteomics, has contributed to a deeper exploration of the pathogenesis and biomarkers of SLE, facilitating precision diagnosis and treatment. This review summarizes the latest research data and achievements in SLE for the years 2021-2022, providing an overview and summary of relevant studies conducted in the past two years.
系统性红斑狼疮（SLE）是一种影响多个器官系统的自身免疫性疾病，临床表现复杂多样。SLE异质性的治疗反应和预后对其诊断、分类及同质化治疗构成了重大挑战。合成生物学、基因组学和蛋白质组学等新技术和领域的出现，有助于更深入地探索SLE的发病机制和生物标志物，推动精准诊断和治疗。本综述总结了2021年至2022年SLE的最新研究数据和成果，对过去两年开展的相关研究进行了概述和总结。
