Mohit-Tabatabai M A, Sobel H J, Rush B F, Mashberg A
Am J Surg. 1986 Oct;152(4):351-3. doi: 10.1016/0002-9610(86)90303-x.
We have reviewed the clinical course and histologic findings in 84 patients with stage I and II squamous carcinoma of the mouth floor. We concluded that lesion thickness may offer a useful method for predicting the probability of cervical metastasis in node negative (N0) patients. Moreover, surface area of the lesion did not correlate with subsequent nodal disease, whereas thickness did. Elective node dissection appears to be strongly indicated in any patient with a N0 lesion measuring more than 1.5 mm in thickness.
我们回顾了84例I期和II期口底鳞状细胞癌患者的临床病程及组织学检查结果。我们得出结论，病灶厚度可能为预测淋巴结阴性（N0）患者发生颈部转移的可能性提供一种有用的方法。此外，病灶表面积与随后的淋巴结疾病并无关联，而厚度则有关联。对于任何N0病灶厚度超过1.5毫米的患者，选择性淋巴结清扫术似乎是强烈推荐的。
