Richter Lars, Szalai Alan M, Manzanares-Palenzuela C Lorena, Kamińska Izabela, Tinnefeld Philip
Department of Chemistry and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität München, Butenandtstraße 5-13, Haus E, 81377, München, Germany.
Institute of Physical Chemistry of the Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland.
Adv Mater. 2023 Oct;35(41):e2303152. doi: 10.1002/adma.202303152. Epub 2023 Sep 5.
The world of 2D materials is steadily growing, with numerous researchers attempting to discover, elucidate, and exploit their properties. Approaches relying on the detection of single fluorescent molecules offer a set of advantages, for instance, high sensitivity and specificity, that allow the drawing of conclusions with unprecedented precision. Herein, it is argued how the study of 2D materials benefits from fluorescence-based single-molecule modalities, and vice versa. A special focus is placed on DNA, serving as a versatile adaptor when anchoring single dye molecules to 2D materials. The existing literature on the fruitful combination of the two fields is reviewed, and an outlook on the additional synergies that can be created between them provided.
二维材料的世界正在稳步发展，众多研究人员试图发现、阐明并利用其特性。依靠单个荧光分子检测的方法具有一系列优势，例如高灵敏度和特异性，这使得能够以前所未有的精度得出结论。本文阐述了二维材料的研究如何受益于基于荧光的单分子模式，反之亦然。特别关注了DNA，它在将单个染料分子锚定到二维材料上时作为一种通用的衔接子。回顾了关于这两个领域卓有成效结合的现有文献，并展望了它们之间可以产生的更多协同效应。
