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免疫功能低下患者的淡紫拟青霉性蜂窝织炎

Paecilomyces lilacinus cellulitis in an immunocompromised patient.

作者信息

Jade K B, Lyons M F, Gnann J W

出版信息

Arch Dermatol. 1986 Oct;122(10):1169-70.

PMID:3767401
Abstract

Paecilomyces lilacinus, a saprophytic soil fungus, is an uncommon human pathogen. An immunocompromised patient developed a deep cellulitis due to P lilacinus. The infection responded poorly to intravenous amphotericin B but eventually resolved after combination therapy with amphotericin B and flucytosine (5-fluorocytosine). Previous in vitro studies have suggested that miconazole is the most active antifungal agent against P lilacinus.

摘要

淡紫拟青霉是一种腐生性土壤真菌,是一种不常见的人类病原体。一名免疫功能低下的患者因淡紫拟青霉引发了深部蜂窝织炎。该感染对静脉注射两性霉素B反应不佳,但在两性霉素B和氟胞嘧啶(5-氟胞嘧啶)联合治疗后最终痊愈。此前的体外研究表明,咪康唑是针对淡紫拟青霉最具活性的抗真菌剂。

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引用本文的文献

1
Antifungal susceptibilities of Paecilomyces species.拟青霉属菌种的抗真菌药敏性
Antimicrob Agents Chemother. 1998 Jul;42(7):1601-4. doi: 10.1128/AAC.42.7.1601.
2
Complicated soft tissue infection with prepatellar bursitis caused by Paecilomyces lilacinus in an immunocompetent host: case report and review.免疫功能正常宿主中由淡紫拟青霉引起的伴有髌前滑囊炎的复杂软组织感染:病例报告及文献复习
J Clin Microbiol. 1996 Jun;34(6):1559-62. doi: 10.1128/jcm.34.6.1559-1562.1996.
3
Fungal infections of the immunocompromised host: clinical and laboratory aspects.
免疫功能低下宿主的真菌感染:临床与实验室方面
Clin Microbiol Rev. 1988 Oct;1(4):349-64. doi: 10.1128/CMR.1.4.349.
4
Hyalohyphomycosis caused by Paecilomyces variotii: a case report, animal pathogenicity and 'in vitro' sensitivity.由变幻青霉引起的透明丝孢霉病:一例报告、动物致病性及“体外”敏感性
Antonie Van Leeuwenhoek. 1992 Oct;62(3):225-30. doi: 10.1007/BF00582583.
5
Paecilomyces lilacinus catheter-related fungemia in an immunocompromised pediatric patient.一名免疫功能低下的儿科患者发生淡紫拟青霉导管相关真菌血症。
J Clin Microbiol. 1992 Sep;30(9):2479-83. doi: 10.1128/jcm.30.9.2479-2483.1992.