Key Laboratory of Efficient Utilization of Nongrain Feed Resources, College of Animal Science and Technology, Shandong Agricultural University, Taian, Shandong, 271018, China.
College of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China.
Sci Data. 2023 Sep 7;10(1):594. doi: 10.1038/s41597-023-02505-4.
Chickens are remarkably versatile animals that are used as model organisms for biomedical research. Here, we performed metabolomic and RNA sequencing (RNA-Seq) transcriptomic analyses of the hypothalamus, liver tissue and serum of poultry with different genetic backgrounds, providing detailed information for hypothalamus and liver tissue at the transcriptional level and for liver tissue and serum at the metabolite level. We present two datasets generated from 36 samples from three poultry breeds using high-throughput RNA-Seq and liquid chromatography coupled with mass spectrometry acquisition (LC/MS). The transcriptomic and metabolomic data obtained for poultry of different genetic backgrounds will be a valuable resource for further studies on this model organism.
鸡是一种非常多才多艺的动物，被用作生物医学研究的模式生物。在这里，我们对具有不同遗传背景的家禽的下丘脑、肝脏组织和血清进行了代谢组学和 RNA 测序（RNA-Seq）转录组学分析，为下丘脑和肝脏组织提供了转录水平的详细信息，为肝脏组织和血清提供了代谢物水平的详细信息。我们展示了使用高通量 RNA-Seq 和液相色谱-质谱联用（LC/MS）采集从三个家禽品种的 36 个样本生成的两个数据集。不同遗传背景家禽的转录组学和代谢组学数据将成为进一步研究该模式生物的宝贵资源。
