Shinagawa E, Matsushita K, Nonobe M, Adachi O, Ameyama M, Ohshiro Y, Itoh S, Kitamura Y
Biochem Biophys Res Commun. 1986 Sep 30;139(3):1279-84. doi: 10.1016/s0006-291x(86)80316-3.
Availability of different analogues of pyrroloquinoline quinone as the prosthetic group for apo-D-glucose dehydrogenase was examined. The 9-carboxyl group of pyrroloquinoline quinone was shown to be essential for the reconstitution of the enzyme activity. Although the carboxyl group may not be involved in catalytic function, it is quite probable to contribute the binding of the prosthetic group to apoenzyme.
研究了不同的吡咯喹啉醌类似物作为脱辅基-D-葡萄糖脱氢酶辅基的可用性。结果表明，吡咯喹啉醌的9-羧基对于酶活性的重建至关重要。虽然羧基可能不参与催化功能，但它很可能有助于辅基与脱辅基酶的结合。
