Vila Jorge A
IMASL-CONICET, Universidad Nacional de San Luis, Ejército de Los Andes 950, 5700 San Luis, Argentina.
Biophys Rev. 2023 Aug 4;15(4):439-445. doi: 10.1007/s12551-023-01107-z. eCollection 2023 Aug.
A comparative analysis between two problems-apparently unrelated-which are solved in a period of ~400 years, viz., the accurate prediction of both the planetary orbits and the protein structures, leads to inferred conjectures that go far beyond the existence of a common path in their resolution, i.e., observation → pattern recognition → modeling. The preliminary results from this analysis indicate that complementary science, together with a new perspective on protein folding, may help us discover common features that could contribute to a more in-depth understanding of still-unsolved problems such as protein folding.
对两个明显不相关的问题进行比较分析,这两个问题在约400年的时间里得到了解决,即对行星轨道和蛋白质结构的精确预测,由此得出的推测远远超出了它们在解决过程中存在共同路径这一范畴,也就是观察→模式识别→建模。该分析的初步结果表明,互补科学以及对蛋白质折叠的新视角,可能有助于我们发现共同特征,从而更深入地理解诸如蛋白质折叠等尚未解决的问题。