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韩国老年人的肌肉减少症与贫血:一项基于全国人口的研究。

Sarcopenia and Anemia in Elderly Koreans: A Nationwide Population-Based Study.

作者信息

Lee Do-Youn, Shin Sunghoon

机构信息

Research Institute of Human Ecology, Yeungnam University, Gyeongsan 38541, Republic of Korea.

Neuromuscular Control Laboratory, Yeungnam University, Gyeongsan 38541, Republic of Korea.

出版信息

Healthcare (Basel). 2023 Aug 30;11(17):2428. doi: 10.3390/healthcare11172428.

Abstract

Sarcopenia and anemia are common diseases in the elderly and are caused by various factors. In this study, the association between sarcopenia and anemia in an elderly Korean population was examined. The Korea Centers for Disease Control and Prevention's cross-sectional, nationally representative Korea National Health and Nutrition Examination Survey (KNHANES, 2008-2011) served as the source of the data for this study. Of the 2769 participants (1167 men and 1602 women) included in this study, a significant association was found between sarcopenia and anemia in the elderly in Korea. In Model 1, unadjusted for covariates, the prevalence of sarcopenia in all participants was 1.805 (95% CI 1.364-2.388) and 2.746 (95% CI 1.740-4.334) in men, and 1.494 (95% CI 1.045-2.138) in women. In Model 4, adjusted for all covariates, the prevalence of sarcopenia in all participants was 1.455 (95% CI 1.064-1.989) and 2.649 (95% CI 1.475-4.755) in men, but it was insignificant in women. While prior studies failed to consider variables such as exercise status and nutritional intake, this research incorporated these factors as covariates. Despite this comprehensive approach, this study still revealed an independent association between sarcopenia and anemia. Moreover, a significant association was uncovered among elderly men, with no corresponding association identified among women.

摘要

肌肉减少症和贫血是老年人的常见疾病,由多种因素引起。在本研究中,对韩国老年人群中肌肉减少症与贫血之间的关联进行了调查。韩国疾病控制与预防中心具有全国代表性的横断面韩国国民健康与营养检查调查(KNHANES,2008 - 2011年)作为本研究的数据来源。在本研究纳入的2769名参与者(1167名男性和1602名女性)中,发现韩国老年人的肌肉减少症与贫血之间存在显著关联。在模型1中,未对协变量进行调整时,所有参与者中肌肉减少症的患病率在男性中为1.805(95%置信区间1.364 - 2.388),在女性中为1.494(95%置信区间1.045 - 2.138)。在模型4中,对所有协变量进行调整后,所有参与者中肌肉减少症的患病率在男性中为1.455(95%置信区间1.064 - 1.989),在女性中为2.649(95%置信区间1.475 - 4.755),但在女性中不显著。虽然先前的研究未考虑运动状态和营养摄入等变量,但本研究将这些因素纳入协变量。尽管采用了这种综合方法,本研究仍揭示了肌肉减少症与贫血之间的独立关联。此外,在老年男性中发现了显著关联,而在女性中未发现相应关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d05e/10487604/cab5bfce3d64/healthcare-11-02428-g001.jpg

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