Fiber and Biopolymer Research Institute, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX 79409, USA.
Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Molecules. 2023 Aug 31;28(17):6381. doi: 10.3390/molecules28176381.
Bleached and cationized cotton fabrics were chemically modified with reactive organoselenium compounds through the nucleophilic aromatic substitution (SAr) reaction, which allowed for organo-selenium attachment onto the surface of cotton fabrics via covalent bonds and, in the case of the cationized cotton fabric, additional ionic interactions. The resulting textiles exhibited potent bactericidal activity against (99.99% reduction), although only moderate activity was observed against . Fabrics treated with reactive organo-selenium compounds also exhibited fungicidal activities against , and much higher antifungal activity was observed when organo-selenium compounds were applied to the cationized cotton in comparison to the bleached cotton. The treatment was found to be durable against rigorous washing conditions (non-ionic detergent/100 °C). This paper is the first report on a novel approach integrating the reaction of cotton fabrics with an organo-selenium antimicrobial agent. This approach is attractive because it provides a method for imparting antimicrobial properties to cotton fabrics which does not disrupt the traditional production processes of a textile mill.
经过亲核芳香取代（SAr）反应，漂白和阳离子化棉织物被用反应性有机硒化合物进行化学修饰，这使得有机硒可以通过共价键附着在棉织物表面上，对于阳离子化棉织物，还可以通过额外的离子相互作用。结果表明，这些纺织品对具有很强的杀菌活性（减少 99.99%），尽管对的活性仅为中度。用反应性有机硒化合物处理的织物还对具有杀菌活性，并且与漂白棉相比，将有机硒化合物应用于阳离子化棉时观察到更高的抗真菌活性。该处理方法被发现可耐受苛刻的洗涤条件（非离子洗涤剂/100°C）。本文首次报道了一种将棉织物与有机硒抗菌剂反应相结合的新方法。这种方法很有吸引力，因为它为棉织物赋予了抗菌性能，而不会破坏纺织厂的传统生产工艺。
