Wiedermann C J, Goldman M E, Pert C B
Cell Tissue Kinet. 1986 Jul;19(4):467-70. doi: 10.1111/j.1365-2184.1986.tb00744.x.
Gastrin-releasing peptide and the carboxyterminal fragments gastrin-releasing peptide [14-27] and [18-27] are found by radioimmunology and high performance liquid chromatography to be present in heat-inactivated fetal calf sera. Peptides containing the carboxyterminal sequence of gastrin-releasing peptide are known to display mitogenic activity. Thus, gastrin-releasing peptide represents a new class of mitogenic factors that are present in heat-inactivated fetal calf serum.
通过放射免疫分析法和高效液相色谱法发现，胃泌素释放肽及其羧基末端片段胃泌素释放肽[14 - 27]和[18 - 27]存在于热灭活的胎牛血清中。已知含有胃泌素释放肽羧基末端序列的肽具有促有丝分裂活性。因此，胃泌素释放肽代表了一类存在于热灭活胎牛血清中的新型促有丝分裂因子。
