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单次体外冲击波碎石术治疗单个直径为10至20毫米肾结石后结石清除率的预测因素:一家私立中心的经验

Predictors of stone-free rate after a single-session extracorporeal shockwave lithotripsy for a single kidney stone measuring 10 to 20 mm: A private center experience.

作者信息

Faddan Amr A, Najieb Osama, Gadelkareem Rabea A

机构信息

Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Assiut, Egypt.

Health Insurance Hospital, Ministry of Health, Mallawy, Egypt.

出版信息

Curr Urol. 2023 Mar;17(1):30-35. doi: 10.1097/CU9.0000000000000152. Epub 2022 Sep 16.

Abstract

BACKGROUND

Despite the continuous update of guidelines for the management of kidney stones, the ability to predict a successful response to extracorporeal shockwave lithotripsy (SWL) remains a topic of research. This is due to the need to refine the decision making in the context of technological advancements and current pandemics. This study aimed to determine the predictors of stone-free rate (SFR) after single-session SWL in adult patients with a single kidney stone 10 to 20 mm in diameter.

MATERIALS AND METHODS

A retrospective review of the records of patients with a single kidney stone 10 to 20 mm in diameter was performed at a private SWL center from December 2019 to February 2021. Univariate and multivariate analyses were performed for stone- and patient-related factors, using the Student and Mann-Whitney tests for the quantitative variables and the Fisher exact and Pearson correlation tests for the qualitative variables.

RESULTS

A total of 138 patients were eligible for this study, including 92 men and 46 women. The mean age was 38.6 ± 12.4 years, and the mean body mass index (BMI) was 25.9 ± 3.4 kg/m. Four weeks after SWL, 120 patients (87%) were free of stones, and 18 (13%) needed further treatment. Univariate analyses showed that SFR was negatively correlated with increased BMI ( = 0.0001), maximum stone length ( = 0.0001), transverse diameter of the stone ( = 0.0001), number of shocks per session ( = 0.052), and Hounsfield unit (HU) ( = 0.0001). Multivariate analysis revealed that HU ( = 0.009), maximum stone length ( = 0.01), BMI ( = 0.000), and presence of double-J stent ( = 0.034) were independent risk factors for failure of single-session SWL in the treatment of kidney stones 10 to 20 mm in diameter. The estimated average cost per case was USD 450.5.

CONCLUSIONS

Increased HU, maximum stone length, BMI, and presence of double-J stents were independent risk factors for low SFR after single-session SWL for a kidney stone 10 to 20 mm in diameter. The cost of SWL remains an advantage in the private sector.

摘要

背景

尽管肾结石管理指南不断更新,但预测体外冲击波碎石术(SWL)成功疗效的能力仍是一个研究课题。这是因为在技术进步和当前疫情背景下需要优化决策。本研究旨在确定直径为10至20毫米的单发性肾结石成年患者单次SWL术后结石清除率(SFR)的预测因素。

材料与方法

对2019年12月至2021年2月在一家私立SWL中心接受治疗的直径为10至20毫米的单发性肾结石患者的记录进行回顾性分析。对结石相关因素和患者相关因素进行单因素和多因素分析,定量变量采用Student检验和Mann-Whitney检验,定性变量采用Fisher精确检验和Pearson相关检验。

结果

共有138例患者符合本研究条件,其中男性92例,女性46例。平均年龄为38.6±12.4岁,平均体重指数(BMI)为25.9±3.4kg/m²。SWL术后四周,120例患者(87%)结石清除,18例(13%)需要进一步治疗。单因素分析显示,SFR与BMI升高(P = 0.0001)、结石最大长度(P = 0.0001)、结石横径(P = 0.0001)、每次治疗的冲击次数(P = 0.052)和Hounsfield单位(HU)(P = 0.0001)呈负相关。多因素分析显示,HU(P = 0.009)、结石最大长度(P = 0.01)、BMI(P = 0.000)和双J支架的存在(P = 0.034)是直径为10至20毫米的肾结石单次SWL治疗失败的独立危险因素。估计每例平均费用为450.5美元。

结论

HU升高、结石最大长度、BMI和双J支架的存在是直径为10至20毫米的肾结石单次SWL术后SFR低的独立危险因素。在私立部门,SWL的费用仍是一个优势。

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