Wroblewski B M
Clin Orthop Relat Res. 1986 Oct(211):103-7.
A prospective study of a one-stage revision of infected cemented total hip arthroplasty was carried out in 102 consecutive cases using acrylic cement with 0.5 g of gentamicin in each 40 g pack as well as systemic and oral antibiotics. Thirty percent had a sinus tract at some stage before the revision. The most common infecting organism was coagulase-negative Staphylococcus, either as a pure growth or in combination with other organisms. The success rate was 91%, with an average follow-up study of three years and two months. The infection persisted in 9% of the cases. In three cases, infection was correlated with some aspect of the revision technique. The method gave a higher success rate than that obtained without the use of an antibiotic-loaded acrylic cement. Combined systemic and oral use of antibiotics appears to reduce the recurrence rate still further.
对102例连续的感染性骨水泥型全髋关节置换一期翻修病例进行了前瞻性研究,使用每40克包装中含0.5克庆大霉素的丙烯酸骨水泥以及全身和口服抗生素。30%的患者在翻修前的某个阶段有窦道。最常见的感染病原体是凝固酶阴性葡萄球菌,可为纯培养或与其他病原体混合感染。成功率为91%,平均随访时间为三年零两个月。9%的病例感染持续存在。3例感染与翻修技术的某些方面有关。该方法的成功率高于未使用含抗生素丙烯酸骨水泥时的成功率。联合使用全身和口服抗生素似乎能进一步降低复发率。