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一例罕见的胫骨远端骨巨细胞瘤病例。

An Unusual Case of Giant Cell Tumor of the Distal Tibia.

作者信息

Mohapatra Ashutosh R, Choudhury Priyam, Patel Pranav S, Malhotra Rohit S, Patil Ankur B

机构信息

Department of Orthopedics, NMMC Hospital, Vashi, Mumbai, Maharashtra, India.

Department of Radiology, Dr. D. Y. Patil Medical College, Pimpri, Pune, Maharashtra, India.

出版信息

J Orthop Case Rep. 2018 Jul-Aug;8(4):29-31. doi: 10.13107/jocr.2250-0685.1144.

Abstract

INTRODUCTION

Giant cell tumors are common in proximal tibia and distal end radius and have a low tendency to recur. They have been treated successfully with excision and cementing or sandwich bone grafting without recurrence. Here, we present a rare case of giant cell tumor (GCT) of the distal tibia treated successfully with no recurrence at the end of 2 years.

CASE REPORT

A 28-year-old female presented with complaints of pain and restricted movement of the right ankle joint since 1 month. There was no history of trauma. On examination, tenderness on the anterior aspect of the right ankle joint with restricted range of motion was found. X-rays revealed a well-defined expansile predominantly lytic lesion in the distal epi-metaphyseal region of the right tibia with minimal periosteal reaction seen along the medial margin. Magnetic resonance imaging revealed an ill-defined expansile lesion involving the epi-metaphyseal end of the lower end of tibia causing cortical breach and having extra-osseous tissue component with the abnormal signal in flexor and extensor group of muscles with the possibility of GCT. Surgery by excision, curettage, and cementation was performed to fill the defect. Histopathology of the tissue showed multinucleated giant cells with a uniform vesicular nucleus and mononuclear cells which were spindle shaped with uniform vesicular nucleus suggestive of GCT.

CONCLUSION

The patient at 2-year follow-up is doing well, walking without any pain, comfortably and with a full range of motion of the ankle joint with no signs of recurrence.

摘要

引言

骨巨细胞瘤常见于胫骨近端和桡骨远端,复发倾向较低。采用切除加骨水泥填充或三明治式骨移植治疗均取得成功,无复发情况。在此,我们报告一例罕见的胫骨远端骨巨细胞瘤,经治疗后2年未复发。

病例报告

一名28岁女性,自1个月前开始出现右踝关节疼痛及活动受限。无外伤史。检查发现右踝关节前方压痛,活动范围受限。X线显示右胫骨远端骨骺-干骺端区域有一界限清晰的膨胀性溶骨性病变,内侧缘可见少量骨膜反应。磁共振成像显示胫骨下端骨骺-干骺端有一界限不清的膨胀性病变,导致皮质破坏,有骨外组织成分,屈肌和伸肌群有异常信号,考虑为骨巨细胞瘤。行切除、刮除及骨水泥填充手术以填补缺损。组织病理显示有多核巨细胞,核呈均匀泡状,还有单核细胞,呈梭形,核呈均匀泡状,提示为骨巨细胞瘤。

结论

患者随访2年情况良好,行走无疼痛,踝关节活动自如,无复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d39/6343573/75c039bf99df/JOCR-8-29-g001.jpg

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