Kang Yun-Mi, Kim Yeon-Ji, Kim Kyungho
Korean Medicine (KM)-Application Center, Korea Institute of Oriental Medicine (KIOM) Daegu 41062, Republic of Korea.
Korean Convergence Medical Science Major, KIOM School, University of Science and Technology (UST) Daejeon 34054, Republic of Korea.
Am J Transl Res. 2023 Aug 15;15(8):5373-5388. eCollection 2023.
Dyslipidemia is a multifactorial disorder that is a causative factor and risk factor for cardiovascular disease. The incidence of dyslipidemia is expected to increase because of the presence of comorbidities. Although several lipid-lowering drugs have been developed and approved, they are not completely effective and are associated with side effects. Traditional herbal medicine (THM) represents an alternative and complementary approach for managing dyslipidemia because of its low toxicity and beneficial effects, such as anti-inflammatory and antioxidant effects. This review focuses on our current understanding of the antidyslipidemic effect of THMs and discusses the associated regulatory mechanisms. The current findings indicate that THM may lead to the development of novel therapeutic regimens for dyslipidemia.
血脂异常是一种多因素疾病，是心血管疾病的致病因素和危险因素。由于合并症的存在，血脂异常的发病率预计会上升。尽管已经研发并批准了几种降脂药物，但它们并不完全有效，且伴有副作用。传统草药因其低毒性和有益作用，如抗炎和抗氧化作用，代表了一种治疗血脂异常的替代和补充方法。本综述重点阐述了我们目前对传统草药抗血脂异常作用的理解，并讨论了相关的调节机制。目前的研究结果表明，传统草药可能会促成血脂异常新治疗方案的开发。
