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患有慢性血栓栓塞性疾病的患者出现的赋形剂肺病。

Excipient Lung Disease in a Patient with Preexisting Chronic Thromboembolic Disease.

作者信息

Giancaspro Gianni, Kligerman Seth J

机构信息

From the Department of Radiology, Jewish General Hospital, 3755 ch de la Côte-Sainte-Catherine, Montreal, QC, Canada H3T 1E2 (G.G.); and Department of Radiology, National Jewish Health, Denver, Colo (S.J.K.).

出版信息

Radiol Cardiothorac Imaging. 2023 Jul 13;5(4):e230059. doi: 10.1148/ryct.230059. eCollection 2023 Aug.

Abstract

Excipient lung disease is an uncommon condition that occurs when crushed oral tablets are injected intravenously and cause pulmonary hypertension. Diagnosis requires a high degree of clinical suspicion and recognition of characteristic imaging findings. The authors present a previously unreported combination of findings in a patient with excipient lung disease and preexisting chronic thromboembolic disease. A pattern of diffuse centrilobular nodules with sparing of lung segments with chronically occluded pulmonary arteries was highly suggestive of the diagnosis and indicated a vascular cause. Pathologic specimen obtained at the time of pulmonary thromboendarterectomy helped confirm the clinically suspected entity. Pulmonary Arteries, Embolism/Thrombosis, Foreign Bodies, Lung Supplemental material is available for this article. © RSNA, 2023.

摘要

辅料性肺病是一种罕见疾病,发生于静脉注射碾碎的口服片剂并导致肺动脉高压时。诊断需要高度的临床怀疑以及对特征性影像学表现的认识。作者报告了一名患有辅料性肺病及既往慢性血栓栓塞性疾病患者的一组此前未报道的检查结果。弥漫性小叶中心性结节且慢性闭塞性肺动脉所在肺段未受累的表现强烈提示了诊断,并表明存在血管性病因。肺血栓内膜剥脱术时获取的病理标本有助于证实临床怀疑的疾病实体。肺动脉、栓塞/血栓形成、异物、肺 本文有补充材料。© RSNA,2023 年。

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