Dabbagh Rufaidah, Alsulimani Aseel, Alshamrani Sarah, Abuhaimed Alanoud, Alzaid Wejdan, Aldofyan Munirah, Alqahtani Samar, Alsharqi Abdullah, Rawson Richard
Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Department of Family and Community Medicine, King Saud University Medical City, Riyadh, Saudi Arabia.
Saudi Pharm J. 2023 Oct;31(10):101764. doi: 10.1016/j.jsps.2023.101764. Epub 2023 Aug 25.
The trends of prescription opioid misuse are understudied in Arab populations, let alone among university students. Additionally, little is known about the psychological traits that increase susceptibility for such behaviors in this region. Thus, this study aimed to assess the prevalence of prescription opioid misuse and its association with addiction susceptibility, as measured by the Substance Abuse Risk Profile Scale (SURPS).
We sampled university students from King Saud University's women's campus. Data on prescription opioid misuse, SURPS traits, and demographic characteristics were collected using an electronic self-administered survey.
Lifetime prescription opioid misuse was 48.5%, while past-month misuse was 28.9%. On average, SURPS subscale scores for impulsivity (mean = 11.6; SD = 2.8) hopelessness (mean = 12.3; SD = 3.5), sensation seeking (mean = 16.4; SD = 3.8), and anxiety sensitivity (mean = 14.6; SD = 2.6). Anxiety sensitivity composite scores significantly differed between students reporting misuse and those who did not. Moreover, the odds for prescription opioid misuse increased by 7% for every 1 unit increase in anxiety sensitivity (AOR = 1.07; 95% CI = 1.00, 1.14), when controlling for other SURPS measures and student characteristics.
The prevalence of prescription opioid misuse in our study is higher than what is reported in global student populations. This may reflect unmonitored availability of controlled substances and unsupervised medical prescriptions. Additionally, high levels of anxiety sensitivity may be driving such misuse. Further surveillance of prescription drug misuse among university students and motivators for such behavior is needed for planning prevention and control interventions.
阿拉伯人群中处方阿片类药物滥用的趋势研究不足，更不用说大学生群体了。此外，对于该地区增加此类行为易感性的心理特征知之甚少。因此，本研究旨在评估处方阿片类药物滥用的患病率及其与成瘾易感性的关联，成瘾易感性通过药物滥用风险概况量表（SURPS）来衡量。
我们从沙特国王大学女子校区抽取大学生作为样本。通过电子自填式调查问卷收集有关处方阿片类药物滥用、SURPS特征和人口统计学特征的数据。
终生处方阿片类药物滥用率为48.5%，过去一个月的滥用率为28.9%。冲动性（平均值 = 11.6；标准差 = 2.8）、绝望感（平均值 = 12.3；标准差 = 3.5）、寻求刺激（平均值 = 16.4；标准差 = 3.8）和焦虑敏感性（平均值 = 14.6；标准差 = 2.6）的SURPS子量表得分平均而言如此。报告有滥用行为的学生和未报告有滥用行为的学生之间，焦虑敏感性综合得分存在显著差异。此外，在控制其他SURPS指标和学生特征后，焦虑敏感性每增加1个单位，处方阿片类药物滥用的几率就增加7%（调整后比值比 = 1.07；95%置信区间 = 1.00，1.14）。
我们研究中处方阿片类药物滥用的患病率高于全球学生群体的报告水平。这可能反映了管制药品的无监管供应和无监督的医疗处方情况。此外，高水平的焦虑敏感性可能促使了此类滥用行为。需要对大学生中处方药滥用情况及其行为动机进行进一步监测，以规划预防和控制干预措施。
