Biotechnology and Bioprocess Centre of Excellence, Addis Ababa Science and Technology University, Addis Ababa, Ethiopia.
Department of Biotechnology, College of Natural and Applied Sciences, Addis Ababa Science and Technology University, P.O. BOX 16417, Addis Ababa, Ethiopia.
Sci Rep. 2023 Sep 11;13(1):14998. doi: 10.1038/s41598-023-41824-9.
Recently, an interest has surged in incorporating extracts of medicinal plants as active ingredients in cosmetic formulations, highlighting the need to analyze medicinal plants of cosmetic interest for phytochemicals and bioactivities. The tuber of the Ethiopian medicinal plant Impatiens tinctoria A. Rich (Ensosila) is used to make traditional cosmetics. The aim of the study was to investigate the antioxidant and mineral content of the Impatiens tinctoria tuber. Water, ethanol, and methanol were used during the extraction process. High phenolic content was found in methanol extract (107.8 ± 0.025 µg/ml GAE) followed by water extract (92.4 ± 0.02 µg/ml GAE). High flavonoid content was also obtained in methanol extract (136.7 ± 0.04 µg/ml QE). Strong 2,2-diphenyl-1-picryl-hydrazyl (DPPH) scavenging activity was recorded for methanol extract with IC50 value of 44.4 µg/ml, compared with ethanol extract (97.54 µg/ml) and water extracts (98.24 µg/ml). The lower IC50 value of methanolic extract demonstrated strong antioxidant activity. The three elements that were most prevalent in Impatiens tinctoria tuber out of the eight elements examined were K (170 ± 0.05 mg/100 g sample), Ca (87 ± 0.08 mg/100 g sample), and Mg (16 ± 0.01 mg/100 g sample). The phenolics, flavonoids, and minerals found in Impatiens tinctoria A. Rich (Ensosila) tuber may protect against oxidative stress-related skin damage and thus deserving attention for future applications in cosmetics formulations.
最近，人们对将药用植物提取物作为活性成分纳入化妆品配方的兴趣日益浓厚，这凸显了分析具有美容潜力的药用植物的植物化学成分和生物活性的必要性。埃塞俄比亚药用植物 Impatiens tinctoria A. Rich（ Ensosila ）的块茎被用于制作传统化妆品。本研究旨在研究 Impatiens tinctoria 块茎的抗氧化和矿物质含量。在提取过程中使用了水、乙醇和甲醇。甲醇提取物的酚类含量最高（107.8±0.025µg/ml GAE），其次是水提取物（92.4±0.02µg/ml GAE）。甲醇提取物的黄酮类含量也很高（136.7±0.04µg/ml QE）。甲醇提取物对 2,2-二苯基-1-苦基肼（DPPH）的清除活性最强，IC50 值为 44.4µg/ml，而乙醇提取物（97.54µg/ml）和水提取物（98.24µg/ml）的 IC50 值较高。甲醇提取物的 IC50 值较低，表明其具有较强的抗氧化活性。在所研究的 8 种元素中，K（170±0.05mg/100g 样品）、Ca（87±0.08mg/100g 样品）和 Mg（16±0.01mg/100g 样品）是在 Impatiens tinctoria 块茎中含量最高的三种元素。Impatiens tinctoria A. Rich（Ensosila）块茎中发现的酚类、类黄酮和矿物质可能有助于预防与氧化应激相关的皮肤损伤，因此值得关注，未来可将其应用于化妆品配方中。
