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无症状菌尿与糖化血红蛋白A1

Asymptomatic bacteriuria and hemoglobin A1.

作者信息

Schmitt J K, Fawcett C J, Gullickson G

出版信息

Diabetes Care. 1986 Sep-Oct;9(5):518-20. doi: 10.2337/diacare.9.5.518.

DOI:10.2337/diacare.9.5.518
PMID:3769720
Abstract

We measured hemoglobin A1 (HbA1) and performed clean-catch urine cultures in 752 patients (411 men and 341 women) with non-insulin-dependent diabetes mellitus (NIDDM) attending an outpatient diabetes clinic. Prevalence of bacteriuria was significantly greater in diabetic women than in controls (9.1 vs. 5.0%, P less than .001) but not in diabetic men. Risk of bacteriuria was not related to level of HbA1 at the time of urine culture. However, mean duration of diabetes mellitus was significantly greater in diabetic women with bacteriuria than in those without infection (9.9 +/- 1.5 vs. 5.4 +/- 0.4 yr, P less than .025), and the prevalence of bacteriuria was significantly greater in patients with complications of long-standing diabetes mellitus than in those without complications (P less than .005).

摘要

我们对752例(411名男性和341名女性)在门诊糖尿病诊所就诊的非胰岛素依赖型糖尿病(NIDDM)患者进行了糖化血红蛋白A1(HbA1)测量并进行了清洁中段尿培养。糖尿病女性的菌尿患病率显著高于对照组(9.1%对5.0%,P<0.001),但糖尿病男性并非如此。菌尿风险与尿培养时的HbA1水平无关。然而,有菌尿的糖尿病女性的糖尿病平均病程显著长于无感染的女性(9.9±1.5对5.4±0.4年,P<0.025),长期糖尿病并发症患者的菌尿患病率显著高于无并发症患者(P<0.005)。

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