Yin Mingyue, Chen Zhili, Nassis George P, Liu Hengxian, Li Hansen, Deng Jianfeng, Li Yongming
School of Athletic Performance, Shanghai University of Sport, Shanghai, China.
Department of Physical Education, College of Education, United Arab Emirates University, Al Ain, Abu Dhabi, United Arab Emirates.
J Exerc Sci Fit. 2023 Oct;21(4):354-365. doi: 10.1016/j.jesf.2023.08.001. Epub 2023 Sep 1.
to (1) systematically review the chronic effect of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on maximal fat oxidation (MFO) in overweight and obese adults, and (2) explore MFO influencing factors and its dose-response relationships with HIIT and MICT.
Studies using a between-group design involving overweight and obese adults and assessing the effect of HIIT and MICT on MFO were included. A meta-analysis on MFO indices was conducted, and the observed heterogeneities were explored through subgroup, regression, and sensitivity analyses.
Thirteen studies of moderate to high quality with a total of 519 overweight and obese subjects were included in this meta-analysis (HIIT, n = 136; MICT, n = 235; Control, n = 148). HIIT displayed a statistically significant favorable effect on MFO compared to no-training (MD = 0.07; 95%CI [0.03 to 0.11]; = 0%). Likewise, MICT displayed a statistically significant favorable effect on MFO compared to no-training (MD = 0.10; 95%CI [0.06 to 0.15]; = 95%). Subgroup and regression analyses revealed that exercise intensity (Fat vs. non-Fat; %VOpeak), exercise mode, BMI, and VOpeak all significantly moderated MICT on MFO. When analyzing studies that have directly compared HIIT and MCIT in obese people, it seems there is no difference in the MFO change (MD = 0.01; 95%CI [-0.02 to 0.04]; = 64%). No publication bias was found in any of the above meta-analyses (Egger's test > 0.05 for all).
Both HIIT and MICT are effective in improving MFO in overweight and obese adults, and they have similar effects. MCIT with an intensity of 65-70% VOpeak, performed 3 times per week for 60 min per session, will optimize MFO increases in overweight and obese adults. Given the lack of studies examining the effect of HIIT on MFO in overweight and obese adults and the great diversity in the training protocols in the existing studies, we were unable to make sound recommendations for training.
（1）系统评价高强度间歇训练（HIIT）和中等强度持续训练（MICT）对超重和肥胖成年人最大脂肪氧化（MFO）的慢性影响，（2）探讨MFO的影响因素及其与HIIT和MICT的剂量反应关系。
纳入采用组间设计、涉及超重和肥胖成年人并评估HIIT和MICT对MFO影响的研究。对MFO指标进行荟萃分析，并通过亚组分析、回归分析和敏感性分析探讨观察到的异质性。
本荟萃分析纳入了13项质量中等至高的研究，共519名超重和肥胖受试者（HIIT组，n = 136；MICT组，n = 235；对照组，n = 148）。与无训练相比，HIIT对MFO显示出统计学上显著的有益效果（MD = 0.07；95%CI [0.03至0.11]；I² = 0%）。同样，与无训练相比，MICT对MFO也显示出统计学上显著的有益效果（MD = 0.10；95%CI [0.06至0.15]；I² = 95%）。亚组分析和回归分析显示，运动强度（有脂肪代谢与无脂肪代谢；%VO₂peak）、运动模式、BMI和VO₂peak均显著调节MICT对MFO的影响。在分析直接比较肥胖人群中HIIT和MCIT的研究时，MFO变化似乎没有差异（MD = 0.01；95%CI [-0.02至0.04]；I² = 64%）。上述任何荟萃分析均未发现发表偏倚（所有Egger检验P>0.05）。
HIIT和MICT均能有效改善超重和肥胖成年人的MFO，且效果相似。强度为65-70%VO₂peak、每周进行3次、每次60分钟的MCIT将使超重和肥胖成年人的MFO增加达到最佳效果。鉴于缺乏关于HIIT对超重和肥胖成年人MFO影响的研究，且现有研究中的训练方案差异很大，我们无法给出合理的训练建议。
