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印度班加罗尔贾亚纳加尔综合医院抗菌药物预防性使用情况及手术部位感染发生率

Antimicrobial prophylaxis uses and incidence of surgical site infection in Jayanagar General Hospital, Bangalore, India.

作者信息

Allaf Navirian Hassan, Navyashree G A

机构信息

Doctors of Pharmacy, Department of Pharmacy Practice, Nargund College of Pharmacy, Bengaluru, Karnataka, India.

出版信息

J Family Med Prim Care. 2022 Mar;11(3):1179-1183. doi: 10.4103/jfmpc.jfmpc_1068_21. Epub 2022 Mar 10.

Abstract

OBJECTIVE

Wound infections are the commonest hospital-acquired infections in surgical patients. The aim of the present study was to evaluate the pattern of antimicrobial prophylaxis in general surgery in Jayanagar general hospital, Bangalore, India.

METHOD

It is a prospective, observational study. The data were collected from 180 patients who satisfied inclusion and exclusion criteria in Jayanagar General Hospital. During the study, 180 prescriptions were studied and patient records were collected and analyzed using SPSS and Microsoft excel.

RESULT

The patients were taken a crack at the investigation. More frequently used antibiotics are cefotaxime, ceftriaxone, and amikacin. About 98% of patients who undergo minor or major surgery received antibiotics. Among them, 27.22% received amikacin and cefotaxime, 12.22% received ceftriaxone and metronidazole, 12.22% received cefotaxime and metronidazole, and 10.55% received amikacin and ceftriaxone. About 20.5% received the triple combination. Among 180 patients, 37 patients were treated with one antibiotic, 120 patients were treated with two antibiotics, and the rest of 23 patients with three antibiotics and more; among them patients treated with single antibiotics had a high incidence of SSI.

CONCLUSION

The study finished up about the abuse and inappropriate selections of antibiotics. Henceforth, our study likewise proposes following the guidelines for judicious utilization of antibiotics, and limiting inappropriate antibiotic use is the most ideal approach to minimize the odds of SSI. The clinic ought to set up prophylactic antibiotics guidelines which ought to be open and open by each individual from the careful group. The medical checklist ought to be polished viably. Incessant review of prophylactic antibiotic use is expected to improve legitimate practices (prophylactic antibiotics employments). Surgeons should adhere to prophylactic antibiotics guidelines.

摘要

目的

伤口感染是外科患者中最常见的医院获得性感染。本研究的目的是评估印度班加罗尔贾亚纳加尔综合医院普通外科抗菌药物预防的模式。

方法

这是一项前瞻性观察研究。数据收集自贾亚纳加尔综合医院180例符合纳入和排除标准的患者。在研究期间,研究了180份处方,并使用SPSS和Microsoft excel收集和分析患者记录。

结果

患者接受了调查。使用频率较高的抗生素是头孢噻肟、头孢曲松和阿米卡星。约98%接受小手术或大手术的患者使用了抗生素。其中,27.22%的患者使用了阿米卡星和头孢噻肟,12.22%的患者使用了头孢曲松和甲硝唑,12.22%的患者使用了头孢噻肟和甲硝唑,10.55%的患者使用了阿米卡星和头孢曲松。约20.5%的患者接受了三联用药。180例患者中,37例接受单一抗生素治疗,120例接受两种抗生素治疗,其余23例接受三种及以上抗生素治疗;其中接受单一抗生素治疗的患者手术部位感染发生率较高。

结论

该研究发现了抗生素的滥用和不当选择情况。今后,我们的研究同样建议遵循明智使用抗生素的指南,限制不当使用抗生素是降低手术部位感染几率的最理想方法。临床应制定预防性抗生素指南,该指南应由手术团队的每个成员公开查阅。医疗检查表应切实执行。持续审查预防性抗生素的使用情况,以改善合理用药(预防性抗生素的使用)。外科医生应遵守预防性抗生素指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f771/9051696/7812972bc472/JFMPC-11-1179-g001.jpg

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