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星状神经节阻滞可缓解86%的长期新冠症状患者:一项回顾性队列研究

Stellate Ganglion Block Relieves Long COVID-19 Symptoms in 86% of Patients: A Retrospective Cohort Study.

作者信息

Pearson Lisa, Maina Alfred, Compratt Taylor, Harden Sherri, Aaroe Abbey, Copas Whitney, Thompson Leah

机构信息

Pain Management, University of South Florida, Tampa, USA.

Pain Management, Metamorphosis Ltd., Canon City, USA.

出版信息

Cureus. 2023 Sep 13;15(9):e45161. doi: 10.7759/cureus.45161. eCollection 2023 Sep.

DOI:10.7759/cureus.45161
PMID:37711269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10498998/
Abstract

Post-COVID-19 condition, also known as long COVID-19 syndrome and post-acute sequelae of SARS-CoV-2, encompasses an array of symptoms that persist well beyond the initial phase of the viral infection. These symptoms can range in intensity, from mild and manageable to severe and incapacitating. Due to the evolving nature of the SARS-CoV-2 pandemic, treatment protocols for the illness are in a constant state of evolution. The early stage of long COVID-19 syndrome contributes to a dearth of treatment protocols based on empirical evidence, while the absence of a conclusive pathophysiological understanding further complicates the development of such protocols. Current treatment regimens include homeopathic medicine, specialist system-focused treatments, infusion therapies, hyperbaric oxygenation, antivirals, and polypharmacy. The physiological, psychological, and societal impact of long COVID-19 cannot be approached casually and must govern the intensity with which the healthcare community approaches the treatment of long COVID-19 syndrome. In this 41-patient cohort study from a chronic pain management practice, the use of either unilateral or bilateral stellate ganglion block (SGB) was explored to manage symptoms associated with long COVID-19 syndrome. Results indicated that a substantial proportion of patients (86%) experienced a reduction of their symptoms following SGB treatment.

摘要

新冠后状况,也称为新冠长期综合征和新冠病毒2型急性后遗症,包括一系列在病毒感染初始阶段之后仍持续存在的症状。这些症状的严重程度不一,从轻微且可控制到严重且使人丧失能力。由于新冠病毒大流行的不断演变,该疾病的治疗方案也处于持续发展的状态。新冠长期综合征的早期阶段导致基于经验证据的治疗方案匮乏,而缺乏确凿的病理生理学理解进一步使此类方案的制定复杂化。目前的治疗方案包括顺势疗法、以专科系统为重点的治疗、输液疗法、高压氧疗、抗病毒药物以及联合用药。新冠长期综合征对生理、心理和社会的影响不能被随意对待,并且必须指导医疗界治疗新冠长期综合征的力度。在这项来自慢性疼痛管理实践的41例患者队列研究中,探讨了使用单侧或双侧星状神经节阻滞(SGB)来管理与新冠长期综合征相关的症状。结果表明,相当一部分患者(86%)在接受SGB治疗后症状有所减轻。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/10498998/8955d0d55273/cureus-0015-00000045161-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/10498998/8955d0d55273/cureus-0015-00000045161-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/10498998/8955d0d55273/cureus-0015-00000045161-i01.jpg

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A review of cytokine-based pathophysiology of Long COVID symptoms.基于细胞因子的长新冠症状病理生理学综述。
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A Review of Stellate Ganglion Block as an Adjunctive Treatment Modality.星状神经节阻滞作为一种辅助治疗方式的综述
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