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胰腺结核误诊为胰腺囊性肿瘤——一例报告

Misdiagnosis of pancreatic tuberculosis as a pancreatic cystic neoplasm - A case report.

作者信息

Lakmal Kasun, Jayarajah Umesh, Chandraguptha Minidu Ravinda, Nandasena Malith, Pathirana Aloka

机构信息

Department of Surgery, Faculty of Medicine, University of Sri Jayawardenepura, Nugegoda, Sri Lanka.

出版信息

SAGE Open Med Case Rep. 2023 Sep 12;11:2050313X231200289. doi: 10.1177/2050313X231200289. eCollection 2023.

DOI:10.1177/2050313X231200289
PMID:37711963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10498687/
Abstract

Pancreatic tuberculosis is an extremely rare condition. Its non-specific clinical and radiological findings resemble pancreatic malignancy. Here, we report a case of pancreatic tuberculosis that presented with abdominal pain and dyspeptic symptoms for 2 months and was misdiagnosed as a pancreatic cystic neoplasm. Abdominal magnetic resonance imaging showed a well-demarcated exophytic lesion with multiple T2 high signals small cystic areas in the anterior superior part of the head of the pancreas measuring 23 × 20 × 28 mm. This patient has undergone laparotomy and excision of the pancreatic mass. Histological examination revealed granulomatous inflammation of a lymph node with caseation, which was pathognomonic of tuberculosis. She was treated for tuberculosis for 6 months and has become symptom free. The diagnosis of pancreatic tuberculosis could be misleading and should be considered when dealing with pancreatic masses in countries with high incidence.

摘要

胰腺结核是一种极其罕见的病症。其非特异性的临床和影像学表现类似于胰腺恶性肿瘤。在此,我们报告一例胰腺结核病例,该患者出现腹痛和消化不良症状达2个月,最初被误诊为胰腺囊性肿瘤。腹部磁共振成像显示,在胰腺头部前上部有一个边界清晰的外生性病变,伴有多个T2高信号的小囊性区域,大小为23×20×28毫米。该患者接受了剖腹手术并切除了胰腺肿块。组织学检查显示淋巴结有肉芽肿性炎症并伴有干酪样坏死,这是结核病的特征性表现。她接受了6个月的抗结核治疗,现已无症状。胰腺结核的诊断可能会产生误导,在结核病高发国家处理胰腺肿块时应考虑到这一疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6a/10498687/a3cfdcd33f0f/10.1177_2050313X231200289-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6a/10498687/0df73ac21597/10.1177_2050313X231200289-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6a/10498687/a3cfdcd33f0f/10.1177_2050313X231200289-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6a/10498687/0df73ac21597/10.1177_2050313X231200289-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6a/10498687/a3cfdcd33f0f/10.1177_2050313X231200289-fig2.jpg

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Case Rep Surg. 2020 Mar 24;2020:8547526. doi: 10.1155/2020/8547526. eCollection 2020.
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Pancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment.
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United European Gastroenterol J. 2020 May;8(4):396-402. doi: 10.1177/2050640620902353. Epub 2020 Jan 17.
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Nat Rev Gastroenterol Hepatol. 2019 Nov;16(11):676-689. doi: 10.1038/s41575-019-0195-x. Epub 2019 Sep 16.
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Ultrasound imaging features of isolated pancreatic tuberculosis.孤立性胰腺结核的超声成像特征
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