Nguyen Ha Thi Kim, Lee Jiwon, Park Yejin, Park Hyon Jin, Ahn Soon Kil, Kim Jae Kwang, Kang Dong-Ku, Kim Minkyeong, Ahn Chorong, Kim Changmu, Choi Jaehyuk
Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, Korea.
Department of Chemistry, College of Natural Sciences, Incheon National University, Incheon, Korea.
Mycobiology. 2023 Aug 29;51(4):256-263. doi: 10.1080/12298093.2023.2247218. eCollection 2023.
Species in the genus () have been used in natural medicine for a long time. Many studies reported that mycelia or fruiting bodies of spp. exhibited effects of antioxidant, anti-inflammatory, anticancer, and antimicrobial activities. However, comparative analysis in this genus is scarce due to limitation of morphological identification and the sample number. In this study, the 19 strains of seven species were chosen to generate a five-gene-based phylogeny with the 31 global references. In addition, 39 culture extracts were prepared for 13 strains to test for anticancer and antibacterial activities. Strong anticancer activities were found in several extracts from and . Anticancer activities of , cf. and were first described here. The antibacterial ability of and extracts has been confirmed. The antibacterial activities of have been reported at the first time in this study. These results suggest an efficient application of the genus as the drug resources especially for anticancer agents.
（某属）属中的物种长期以来一直被用于天然药物。许多研究报告称，该属物种的菌丝体或子实体具有抗氧化、抗炎、抗癌和抗菌活性。然而，由于形态鉴定和样本数量的限制，该属的比较分析很少。在本研究中，选择了7个该属物种的19个菌株与31个全球参考菌株构建基于五个基因的系统发育树。此外，为13个菌株制备了39种培养提取物，以测试其抗癌和抗菌活性。在来自（某些物种）的几种提取物中发现了很强的抗癌活性。（某些物种）的抗癌活性在此首次描述。（某些物种）提取物的抗菌能力已得到证实。（某些物种）的抗菌活性在本研究中首次报道。这些结果表明该属作为药物资源，特别是抗癌药物的有效应用。
