Genome Analysis of ST1 , a Zoonotic Pathogen Causing Endocarditis in an Elderly Patient in China.

Infective endocarditis (IE) is a rare disease but with high associated mortality. Currently, the mainstays of diagnosis are still echocardiography and blood cultures. Here, we reported a case of infective endocarditis with negative blood cultures, and blood and aortic valve tissue metagenomic next-generation sequencing (mNGS) results suggested . In addition, we obtained the whole genomic sequence of ZJBH strain. To our knowledge, this is the first report of genomic analysis isolated from clinic in China. Furthermore, we described the whole genome sequencing (WGS) data incorporating all from diverse sources worldwide and shed light on underlying risk of transmitted between cats and humans.