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节段性带状疱疹性瘫痪伴霍纳综合征。

Segmental Zoster Paresis Accompanied by Horner's Syndrome.

机构信息

Naka Municipal Kaminaka Hospital, Japan.

Department of Neurology, University of Tokushima Graduate School of Biomedical Sciences, Japan.

出版信息

Intern Med. 2023;62(18):2743-2746. doi: 10.2169/internalmedicine.0578-22. Epub 2023 Sep 15.

DOI:10.2169/internalmedicine.0578-22
PMID:37722924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10569921/
Abstract

We herein report a 90-year-old immunocompromised woman who developed right upper limb weakness and right ptosis with a miotic pupil 1 week after oral therapy for zoster on the right T2 dermatome. The right pupil was dilated with instillation of 1% apraclonidine, indicating Horner's syndrome. The patient was treated with intravenous acyclovir and methylprednisolone. Focal weakness related to zoster, generally known as segmental zoster paresis, improved over five months, but Horner's syndrome remained. We suggest that aggressive intravenous treatment should be considered for rare cases of zoster that occur with a combination of these two neurological conditions.

摘要

我们在此报告一例 90 岁免疫功能低下的女性患者,在右侧 T2 皮节带状疱疹口服治疗 1 周后出现右上肢无力和右侧上睑下垂,伴有瞳孔缩小。右眼瞳孔在滴用 1%阿可乐定后扩大,提示霍纳氏综合征。患者接受了静脉用阿昔洛韦和甲泼尼龙治疗。与带状疱疹相关的局灶性无力,一般称为节段性带状疱疹性瘫痪,在 5 个月内逐渐改善,但霍纳氏综合征仍然存在。我们建议对于这两种神经疾病同时发生的罕见带状疱疹病例,应考虑积极的静脉治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d412/10569921/e2d44e3a2322/1349-7235-62-2743-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d412/10569921/e2d44e3a2322/1349-7235-62-2743-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d412/10569921/e2d44e3a2322/1349-7235-62-2743-g001.jpg

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1
Segmental Zoster Paresis Accompanied by Horner's Syndrome.节段性带状疱疹性瘫痪伴霍纳综合征。
Intern Med. 2023;62(18):2743-2746. doi: 10.2169/internalmedicine.0578-22. Epub 2023 Sep 15.
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本文引用的文献

1
Horner's Syndrome and Segmental Sympathetic Denervation Following Herpes Zoster Brachial Plexopathy.带状疱疹性臂丛神经病后的霍纳综合征和节段性交感神经去神经支配
J Clin Neurol. 2021 Apr;17(2):328-329. doi: 10.3988/jcn.2021.17.2.328.
2
Horner's Syndrome Following Varicella Vaccination.水痘疫苗接种后发生的霍纳综合征。
Neuroophthalmology. 2019 Feb 26;44(4):267-269. doi: 10.1080/01658107.2019.1583759.
3
Clinical Features of Varicella-Zoster Virus Infection.水痘-带状疱疹病毒感染的临床特征。
Viruses. 2018 Nov 2;10(11):609. doi: 10.3390/v10110609.
4
Issues in the Treatment of Neurological Conditions Caused by Reactivation of Varicella Zoster Virus (VZV).水痘带状疱疹病毒(VZV)再激活引起的神经疾病的治疗问题
Neurotherapeutics. 2016 Jul;13(3):509-13. doi: 10.1007/s13311-016-0430-x.
5
Herpes zoster in the T1 dermatome presenting with Horner's syndrome, radicular weakness, and postherpetic neuralgia.T1皮节带状疱疹伴霍纳综合征、神经根性无力和带状疱疹后神经痛。
Int Med Case Rep J. 2008 Oct 8;1:1-2. doi: 10.2147/imcrj.s4008. Print 2008.
6
Adult Horner's syndrome: a combined clinical, pharmacological, and imaging algorithm.成人霍纳综合征:一种综合的临床、药理学和影像学算法。
Eye (Lond). 2013 Mar;27(3):291-8. doi: 10.1038/eye.2012.281. Epub 2013 Feb 1.
7
Current pharmacologic testing for Horner syndrome.目前针对霍纳综合征的药理学检测。
Curr Neurol Neurosci Rep. 2009 Sep;9(5):384-9. doi: 10.1007/s11910-009-0056-z.
8
A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction.一项在引入带状疱疹疫苗之前基于人群的带状疱疹发病率和并发症发生率研究。
Mayo Clin Proc. 2007 Nov;82(11):1341-9. doi: 10.4065/82.11.1341.
9
Recommendations for the management of herpes zoster.带状疱疹管理建议。
Clin Infect Dis. 2007 Jan 1;44 Suppl 1:S1-26. doi: 10.1086/510206.
10
The role of Claude Bernard and others in the discovery of Horner's syndrome.克劳德·伯纳德及其他人在霍纳综合征发现过程中的作用。
J Am Coll Surg. 2004 Dec;199(6):976-80. doi: 10.1016/j.jamcollsurg.2004.06.024.