Gartzke J, Burck D
J Clin Chem Clin Biochem. 1986 Sep;24(9):637-9.
The amounts of total porphyrins, hippuric acid and creatinine, excreted in urine by adult male Wistar rats, exhibited normal distributions for hippuric acid and creatinine, but a bimodal distribution for total porphyrins. This typical distribution of total porphyrins was still observed when creatinine was used as reference parameter. In biochemical and toxicological experiments in rats, the tested parameters should be therefore be investigated for homogeneity.
成年雄性Wistar大鼠尿液中排出的总卟啉、马尿酸和肌酐量，马尿酸和肌酐呈现正态分布，但总卟啉呈现双峰分布。当以肌酐作为参考参数时，仍可观察到总卟啉的这种典型分布。因此，在大鼠的生化和毒理学实验中，应对所测试的参数进行同质性研究。
