Chen Lei, Wang Guo-Zhou, Chi Yuan-Yuan, Zhao Jing
Intensive Care Unit, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Department of Intensive Care Unit, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
World J Clin Cases. 2023 Sep 6;11(25):5870-5877. doi: 10.12998/wjcc.v11.i25.5870.
Young and middle-aged cancer patients in intensive care unit (ICU) often suffer from stress and pressure, causing huge physical and mental damage. Currently, there is few research on post-traumatic stress disorder (PTSD) among young and middle-aged cancer patients in ICU in China, and the psychological status of patients who have experienced both cancer development and ICU stay is still unclear.
To explore the risk factors for PTSD in young and middle-aged patients with cancer in ICU.
Using convenient sampling method, we enrolled 150 young and middle-aged patients with cancer who were admitted to the ICU of our center during the period from July to December 2020. The general data of the patients and PTSD-related indicators were collected. The Impact of Event Scale-Revised (IES-R) was used for assessing PTSD one month after the discharge from the ICU. Binary Logistic regression analysis was performed to assess the independent risk factors for PTSD in these patients.
Among these 150 patients, 32 (21.33%) were found to be with PTSD. Binary Logistic regression analysis revealed that factors significantly associated with PTSD among young and middle-aged patients with cancer in ICU included monthly income (OR = 0.24, = 0.02), planned transfers (OR = 0.208, = 0.019), and Acute Physiology and Chronic Health Evaluation (APACHE II) score (OR = 1.171, = 0.003).
The low monthly income, unplanned transfers, and increased APACHE II score are the risk factors for PTSD in young and middle-aged patients with cancer in ICU.
重症监护病房(ICU)中的中青年癌症患者常承受压力,造成巨大身心损害。目前,国内关于ICU中青年癌症患者创伤后应激障碍(PTSD)的研究较少,经历癌症发展和入住ICU的患者心理状态仍不明确。
探讨ICU中青年癌症患者发生PTSD的危险因素。
采用方便抽样法,选取2020年7月至12月期间入住本中心ICU的150例中青年癌症患者。收集患者的一般资料及PTSD相关指标。采用事件影响量表修订版(IES-R)在患者从ICU出院1个月后评估PTSD。进行二元Logistic回归分析以评估这些患者发生PTSD的独立危险因素。
在这150例患者中,发现32例(21.33%)患有PTSD。二元Logistic回归分析显示,ICU中青年癌症患者中与PTSD显著相关的因素包括月收入(OR = 0.24,P = 0.02)、计划转院(OR = 0.208,P = 0.019)和急性生理与慢性健康状况评分系统(APACHE II)评分(OR = 1.171,P = 0.003)。
月收入低、非计划转院和APACHE II评分升高是ICU中青年癌症患者发生PTSD的危险因素。