Department of Pedodontics and Preventive Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India.
Department of Periodontology, Manipal College of Dental Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India.
ScientificWorldJournal. 2023 Sep 11;2023:9451685. doi: 10.1155/2023/9451685. eCollection 2023.
Silver nanoparticles (AgNPs) release Ag ions with potent bactericidal and anti-inflammatory effects. They have shown promising results as an intracanal medicament for removing (), a resistant bacterium associated with root canal failures. This review summarizes the role of AgNPs as an intracanal medicament. Original research articles on AgNPs as an intracanal medicament were searched in databases such as MEDLINE (PubMed), Scopus, and Embase, resulting in 24 studies. They showed that AgNPs effectively eliminated and reduced postoperative pain following root canal therapy. However, these effects should be further verified through clinical trials as most of the studies were in vitro.
银纳米粒子 (AgNPs) 释放出具有强大杀菌和抗炎作用的银离子。它们已被证明作为一种根管内药物具有很大的潜力，可以去除（），这是一种与根管失败相关的耐药菌。本综述总结了 AgNPs 作为根管内药物的作用。在 MEDLINE（PubMed）、Scopus 和 Embase 等数据库中搜索了关于 AgNPs 作为根管内药物的原始研究文章，共检索到 24 项研究。结果表明，AgNPs 能有效杀灭（），并减少根管治疗后的术后疼痛。然而，由于大多数研究都是在体外进行的，因此这些效果需要通过临床试验进一步验证。
