Department of Electrical, Computer and Biomedical Engineering, Abu Dhabi University, Abu Dhabi, United Arab Emirates.
SDx Tethered Membranes Pty Ltd, Roseville, Sydney, 2069, Australia.
J Membr Biol. 2023 Dec;256(4-6):423-431. doi: 10.1007/s00232-023-00291-z. Epub 2023 Sep 20.
In this study a lipid bilayer membrane model was used in which the bilayer is tethered to a solid substrate with molecular tethers. Voltage-current (V-I) measurements of the tethered bilayer membranes (tBLM) and tBLM with benzyl alcohol (BZA) incorporated in their structures, were measured using triangular voltage ramps of 0-500 mV. The temperature dependence of the conductance deduced from the V-I measurements are described. An evaluation of the activation energies for electrical conductance showed that BZA decreased the activation/ Born energies for ionic conduction of tethered lipid membranes. It is concluded that BZA increased the average pore radius of the tBLM.
在这项研究中，使用了一种脂质双层膜模型，其中双层通过分子系链固定在固体基底上。使用 0-500 mV 的三角形电压斜坡测量了带有苄醇 (BZA) 的固定化双层膜 (tBLM) 和固定化双层膜的电压-电流 (V-I) 测量值。描述了从 V-I 测量得出的电导率与温度的关系。对电导率的活化能的评估表明，BZA 降低了固定化脂质膜离子传导的活化/博恩能。结论是 BZA 增加了 tBLM 的平均孔径。
