Sady S P, Thompson P D, Cullinane E M, Kantor M A, Domagala E, Herbert P N
JAMA. 1986 Nov 14;256(18):2552-5.
We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76% +/- 64%, postheparin lipoprotein lipase activity increased 46% +/- 35%, and fasting triglyceride levels decreased 26% +/- 13% after the race. High-density lipoprotein (HDL) cholesterol level increased 10% +/- 8%, primarily due to a 19% +/- 17% increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus, the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.
我们对10名男性长跑运动员在马拉松比赛前后进行了研究，以确定长时间运动对血清脂蛋白值和清除血浆甘油三酯能力的影响。在比赛前24小时和比赛后18小时测量了血清脂质和脂蛋白浓度、静脉脂肪清除率以及肝素后血浆脂解活性。赛后，外源性脂肪清除率提高了76%±64%，肝素后脂蛋白脂肪酶活性提高了46%±35%，空腹甘油三酯水平降低了26%±13%。高密度脂蛋白（HDL）胆固醇水平提高了10%±8%，主要是由于HDL2亚组分增加了19%±17%。外源性脂肪清除率的变化与HDL胆固醇水平和HDL2亚组分的变化直接相关。因此，长时间运动后HDL胆固醇浓度的升高可能是脂肪清除增强的结果。
