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眼见为实:光学相干断层扫描的发展。

Seeing is believing: The development of optical coherence tomography.

机构信息

Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

出版信息

Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2311129120. doi: 10.1073/pnas.2311129120. Epub 2023 Sep 21.

DOI:10.1073/pnas.2311129120
PMID:37732756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10523475/
Abstract

The 2023 Lasker-DeBakey Clinical Medical Research Award is being presented to James Fujimoto, David Huang, and Eric Swanson for their invention and development of optical coherence tomography (OCT), an imaging technology that uses light to visualize microscopic structures within tissues such as the retina. OCT has dramatically changed the practice of ophthalmology and improved the lives of millions of people. It also has great potential in a wide range of other medical fields.

摘要

2023 年拉斯克-德贝基临床医学研究奖授予詹姆斯·富山、黄大卫和埃里克·斯旺森,以表彰他们发明和开发光学相干断层扫描(OCT)技术。OCT 是一种利用光来可视化组织内微观结构的成像技术,如视网膜。OCT 极大地改变了眼科的实践,并改善了数百万人的生活。它在其他广泛的医学领域也具有巨大的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbfb/10523475/3c0d8590761a/pnas.2311129120fig02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbfb/10523475/d6615be9b529/pnas.2311129120fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbfb/10523475/3c0d8590761a/pnas.2311129120fig02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbfb/10523475/d6615be9b529/pnas.2311129120fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbfb/10523475/3c0d8590761a/pnas.2311129120fig02.jpg

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本文引用的文献

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Artificial intelligence in retinal image analysis: Development, advances, and challenges.视网膜图像分析中的人工智能:发展、进展与挑战
Surv Ophthalmol. 2023 Sep-Oct;68(5):905-919. doi: 10.1016/j.survophthal.2023.04.001. Epub 2023 Apr 26.
2
Optical coherence tomography.光学相干断层扫描
Nat Rev Methods Primers. 2022;2. doi: 10.1038/s43586-022-00162-2. Epub 2022 Oct 13.
3
Optical coherence tomography and coronary revascularization: from indication to procedural optimization.光学相干断层扫描与冠状动脉血运重建:从适应证到操作优化。
Trends Cardiovasc Med. 2023 Feb;33(2):92-106. doi: 10.1016/j.tcm.2021.10.009. Epub 2021 Oct 30.
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Optical coherence tomography in the 2020s-outside the eye clinic.21 世纪 20 年代的光学相干断层扫描——眼科诊室之外。
Eye (Lond). 2021 Jan;35(1):236-243. doi: 10.1038/s41433-020-01263-6. Epub 2020 Nov 9.
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Optical coherence tomography angiography: a review of current and future clinical applications.光学相干断层扫描血管造影术:当前及未来临床应用综述
Graefes Arch Clin Exp Ophthalmol. 2018 Feb;256(2):237-245. doi: 10.1007/s00417-017-3896-2. Epub 2018 Jan 9.
6
Estimating Public and Patient Savings From Basic Research-A Study of Optical Coherence Tomography in Managing Antiangiogenic Therapy.估算基础研究带来的公共及患者节省——光学相干断层扫描在抗血管生成治疗管理中的研究
Am J Ophthalmol. 2018 Jan;185:115-122. doi: 10.1016/j.ajo.2017.09.027. Epub 2017 Dec 7.
7
Cellular Characterization of OCT and Outer Retinal Bands Using Specific Immunohistochemistry Markers and Clinical Implications.使用特定免疫组织化学标志物对 OCT 和外视网膜带进行细胞特征分析及其临床意义。
Ophthalmology. 2018 Mar;125(3):407-422. doi: 10.1016/j.ophtha.2017.09.016. Epub 2017 Oct 13.
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