Zeichner Joshua A, Baldwin Hillary E, Cook-Bolden Fran E, Eichenfield Lawrence F, Fallon-Friedlander Sheila, Rodriguez David A
Mount Sinai Hospital, New York, New York.
Morristown, New Jersey.
J Clin Aesthet Dermatol. 2017 Jan;10(1):37-46. Epub 2017 Jan 1.
Acne vulgaris (acne) is a common affliction in adolescence and is a growing problem in adult women. Despite an increasing awareness of acne in the adult female population, there is a lack of good prospective studies assessing the severity, distribution, and differential response to treatment in this group. The long-held dogma that acne in adult women develops on the lower one-third of the face has been recently challenged, and here the authors critically review data from available literature. Moreover, while adult female acne has traditionally been defined as disease in women over age 25, it is the authors' experience that this group is subdivided into women ages 25 to 44 years, separate from perimenopausal patients, ages 45 years and up. While there is no data specifically comparing these two groups, the authors will review the existing data and provide practical recommendations based on our experience in treating these groups of patients. Finally, while there is a lack of data on this subject, it is the group's opinion that adherence to medication regimens is likely higher in women than men, which influences therapeutic outcomes.
寻常痤疮在青少年中很常见,在成年女性中也是一个日益严重的问题。尽管成年女性人群对痤疮的认识有所提高,但缺乏评估该群体痤疮严重程度、分布情况及对治疗的不同反应的良好前瞻性研究。长期以来认为成年女性痤疮发生在面部下三分之一的观点最近受到了挑战,本文作者对现有文献数据进行了批判性综述。此外,虽然成年女性痤疮传统上被定义为25岁以上女性的疾病,但作者的经验是,该群体可细分为25至44岁的女性,与45岁及以上的围绝经期患者分开。虽然没有数据专门比较这两组,但作者将回顾现有数据,并根据治疗这些患者群体的经验提供实用建议。最后,虽然关于这个主题的数据不足,但该团队认为女性对药物治疗方案的依从性可能高于男性,这会影响治疗效果。