Moholdt Trine, Stanford Kristin I
Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; Department of Gynaecology and Obstetrics, St. Olav's Hospital, Trondheim, Norway.
Dorothy M. Davis Heart and Lung Research Institute, Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Trends Endocrinol Metab. 2024 Jan;35(1):23-30. doi: 10.1016/j.tem.2023.08.019. Epub 2023 Sep 19.
Exercise has systemic health benefits through effects on multiple tissues, with intertissue communication. Recent studies indicate that exercise may improve breastmilk composition and thereby reduce the intergenerational transmission of obesity. Even if breastmilk is considered optimal infant nutrition, there is evidence for variations in its composition between mothers who are normal weight, those with obesity, and those who are physically active. Nutrition early in life is important for later-life susceptibility to obesity and other metabolic diseases, and maternal exercise may provide protection against the development of metabolic disease. Here we summarize recent research on the influence of maternal obesity on breastmilk composition and discuss the potential role of exercise-induced adaptations to breastmilk as a kick-start to prevent childhood obesity.
运动通过对多个组织的影响以及组织间的交流，对全身健康有益。最近的研究表明，运动可能改善母乳成分，从而减少肥胖的代际传递。即使母乳被认为是最佳的婴儿营养，但有证据表明，体重正常的母亲、肥胖母亲和身体活跃的母亲的母乳成分存在差异。生命早期的营养对于后期患肥胖症和其他代谢疾病的易感性很重要，而母亲运动可能对预防代谢疾病的发展起到保护作用。在此，我们总结了近期关于母亲肥胖对母乳成分影响的研究，并讨论了运动诱导的母乳适应性变化在预防儿童肥胖方面作为开端的潜在作用。
