Suppr超能文献

熊去氧胆酸对胆总管结石的保守治疗

The Conservative Management of Choledocholithiasis With Ursodeoxycholic Acid.

作者信息

Oluboyede Daniel O, Zafar Mansoor, Shirazi Farah, Dsouza Kevin, Abdulkarim Abdulmoen, Hacikurt Kadir, Whitehead Mark

机构信息

Internal Medicine, Conquest Hospital, East Sussex Healthcare NHS Trust, St Leonards-on-Sea, GBR.

Gastroenterology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, GBR.

出版信息

Cureus. 2023 Aug 21;15(8):e43850. doi: 10.7759/cureus.43850. eCollection 2023 Aug.

Abstract

Choledocholithiasis has been defined as the presence of stones within the common bile duct (CBD) with up to one-half of the cases remaining asymptomatic. We report a case of an 84-year-old frail male admitted for the treatment of pneumonia, pleural effusion, and bacteraemia with co-incidental deranged liver function tests (LFTs). Ensuing magnetic resonance cholangiopancreatography (MRCP) noted three CBD stones; however, the patient remained asymptomatic. After discussing the benefits and risks of treatment options with the gastroenterology team, the patient refused endoscopic retrograde cholangiopancreatography (ERCP) and opted for close monitoring in the community whilst taking ursodeoxycholic acid (UDCA). In the months following, his LFTs normalised, and repeat MRCP no longer showed stones. This case demonstrates that UDCA with close monitoring may be considered a non-invasive alternative treatment of CBD stones, particularly in elderly or frail patients with multiple comorbidities.

摘要

胆总管结石被定义为胆总管(CBD)内存在结石,多达一半的病例无症状。我们报告一例84岁体弱男性病例,因肺炎、胸腔积液和菌血症入院治疗,同时伴有肝功能检查(LFTs)紊乱。随后的磁共振胰胆管造影(MRCP)发现了3颗胆总管结石;然而,患者仍无症状。在与胃肠病学团队讨论治疗方案的益处和风险后,患者拒绝了内镜逆行胰胆管造影(ERCP),选择在社区密切监测,同时服用熊去氧胆酸(UDCA)。在接下来的几个月里,他的肝功能检查恢复正常,复查MRCP不再显示结石。该病例表明,密切监测下的UDCA可被视为胆总管结石的一种非侵入性替代治疗方法,特别是对于患有多种合并症的老年或体弱患者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验