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用 Duddingtonia flagrans 商业化制剂对马属胃肠道线虫的疗效评价。

Efficacy Evaluation of a Commercial Formulation With Duddingtonia Flagrans in Equine Gastrointestinal Nematodes.

机构信息

Departamento de Medicina Veterinária Preventiva, Laboratório de Bacteriologia (LABAC), Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil.

Universidade do Oeste de Santa Catarina, Xanxerê, Santa Catarina, Brazil.

出版信息

J Equine Vet Sci. 2023 Dec;131:104930. doi: 10.1016/j.jevs.2023.104930. Epub 2023 Sep 20.

Abstract

The indiscriminate use of antiparasitics for the treatment of helminths in horses has caused the ineffectiveness of commonly used chemical active principles, therefore, new alternatives such as the use of helminthophagous fungi have been studied. In this context, this study aimed to evaluate the in vitro efficacy of the commercial formulation Bioverm, composed of the fungus Duddingtonia flagrans strain AC001, in the reduction of gastrointestinal nematode larvae in equine feces. In coproculture, the genus Cyathostomum sp. was the most prevalent in the analyzed samples. The commercial formulation with D. flagrans demonstrated effectiveness in the predation of Cyathostomum sp. in tests. The recommended dose of 0.4 g, containing 10 chlamydospores per gram of product, reduced larvae by 44.23%, while the extrapolated dose of 1.0 g with the same concentrations of chlamydospores (10/g) resulted in a reduction of 57.20%, indicating the effectiveness of the product in controlling infective larvae.

摘要

驱虫剂在马匹中用于治疗蠕虫的无差别使用导致了常用化学活性成分的失效,因此,已经研究了诸如使用食寄生虫真菌等新的替代方法。在这种情况下,本研究旨在评估含有真菌 Duddingtonia flagrans 菌株 AC001 的商业制剂 Bioverm 在减少马粪便中胃肠道线虫幼虫方面的体外功效。在共培养中,Cyathostomum sp. 属在分析样本中最为普遍。含有 10 个厚垣孢子/克产品的推荐剂量 0.4 克对 Cyathostomum sp. 的捕食表现出有效性,减少了 44.23%的幼虫,而相同浓度的厚垣孢子(10/g)的外推剂量 1.0 克导致减少了 57.20%,表明该产品在控制感染性幼虫方面的有效性。

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