Recent Progress in the Synthesis of Silaspiranes.
作者信息
Chen Hua, Hu Xuejiao, Wang Wanshu, Gao Lu, Song Zhenlei
机构信息
College of Pharmaceutical Science and, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, 310014, Hangzhou, P. R. China.
Key Laboratory of Drug-Targeting and, Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, 610064, Chengdu, P. R. China.
出版信息
Chemistry. 2023 Dec 14;29(70):e202302371. doi: 10.1002/chem.202302371. Epub 2023 Oct 31.
Silaspiranes bearing a spiro-silicon center are promising ring frameworks for the synthesis of novel spirocyclic molecules possessing unique properties. Development of efficient methods towards these ring structures has therefore attracted considerable attentions of synthetic chemists. This minireview highlights the representative advances in the field, and is categorized into four parts according to the ring formation strategies: cyclization, annulation, ring expansion and cycloaddition.
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