Unité de recherche: Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie.
National Center of biotechnology Research, Constantine, Algérie.
Nat Prod Res. 2024 Nov;38(21):3842-3847. doi: 10.1080/14786419.2023.2261073. Epub 2023 Sep 23.
The phytochemical investigation of both chloroform and ethyl acetate extracts of DC from an Algerian endemic plant led to the isolation of a new isoflavonoid Aspalathoidin compound () and nine known compounds (laburnetin, isokaempferide, retamasin B, ephedrodin, sakuretin, isoprunetin, genistein -7--β-glucoside, derrone-4'--methyl ether and eriodictyol-7,3'-dimethylether). Twelve phenolic compounds were identified in ethyl acetate and -butanol extracts through a qualitative investigation of phenolic compounds using HPLC. Finally, both extracts were estimated for their phenolic and flavonoid contents as well as the evaluation of their antioxidant activity using five different assays DPPH, CUPRAC, ABTS, GOR and the sun protection factor SPF was determined as an index of the photoprotective capacity of the DC extracts. The extract of chloroform and ethyl acetate has good antioxidant and includes significant levels of phenolic and flavonoid components.
对来自阿尔及利亚特有植物的 DC 的氯仿和乙酸乙酯提取物进行植物化学研究，分离得到一种新的异黄酮 Aspalathoidin 化合物（）和 9 种已知化合物（金雀花素、异坎皮弗瑞德、雷塔马林 B、麻黄素、沙库雷丁、异普瑞汀、染料木素-7--β-葡萄糖苷、德龙-4'-甲基醚和埃罗蒂二醇-7,3'-二甲醚）。通过 HPLC 对酚类化合物进行定性分析，在乙酸乙酯和正丁醇提取物中鉴定出 12 种酚类化合物。最后，分别用 5 种不同的方法测定二氯甲烷和乙酸乙酯提取物的总酚和总黄酮含量，并评估其抗氧化活性，以 DPPH、CUPRAC、ABTS、GOR 测定值和防晒系数（SPF）作为二氯甲烷和乙酸乙酯提取物光保护能力的指标。氯仿和乙酸乙酯提取物具有良好的抗氧化活性，且含有大量的酚类和类黄酮成分。
