Twardowski Z J, Khanna R, Nolph K D, Scalamogna A, Metzler M H, Schneider T W, Prowant B F, Ryan L P
Nephron. 1986;44(2):129-35. doi: 10.1159/000184217.
Intraabdominal pressures were measured during natural activities in 6 men, age 24-62 years, treated with continuous ambulatory peritoneal dialysis. The pressures were measured with a pressure transducer secured at the level of the umbilicus in the supine, sitting, and upright positions with 0-3 liters intraperitoneal fluid during talking, coughing, straining, changing position, walking, jogging, exercycling, jumping and weight lifting. Coughing and straining generated the highest intraabdominal pressures in every position. The pressures with weight lifting were proportional to the magnitude of the weight lifted up to 50 lbs, but were lower than those during coughing and straining. The pressures were generally higher with greater intraabdominal fluid volumes, especially with jumping and coughing. Exercycling was associated with lower intraabdominal pressure than was jogging, and the pressures were only minimally influenced by intraperitoneal fluid volumes. The results of this study can be used as a guide in establishing preventive measures in patients with intraperitoneal fluid to decrease complication rates related to raised intraabdominal pressures such as dialysate leaks, hernias and hemorrhoids.
对6名年龄在24至62岁、接受持续性非卧床腹膜透析治疗的男性患者在自然活动期间测量腹腔内压力。在仰卧位、坐位和直立位时，于脐水平用压力传感器测量压力，腹腔内注入0至3升液体，测量在交谈、咳嗽、用力、改变体位、行走、慢跑、骑健身车、跳跃和举重过程中的压力。在每个体位下，咳嗽和用力时产生的腹腔内压力最高。举重时的压力与所举重量大小成正比，最大至50磅，但低于咳嗽和用力时的压力。腹腔内液体量越大，压力通常越高，尤其是在跳跃和咳嗽时。骑健身车时的腹腔内压力低于慢跑时，且压力仅受腹腔内液体量的轻微影响。本研究结果可作为制定预防措施的指导，用于腹腔内有液体的患者，以降低与腹腔内压力升高相关的并发症发生率，如透析液渗漏、疝气和痔疮。
