Department of Preventive Medicine and Public Health, Keio University School of Medicine.
Research Center for Social Studies of Health and Community Ritsumeikan University.
J Epidemiol. 2024 Jun 5;34(6):265-269. doi: 10.2188/jea.JE20220226. Epub 2024 Feb 29.
Whether smoking is associated with worse quality of life (QoL) or not is relatively controversial. The current study is to investigate the relationship between smoking and subjective QoL in a long cohort study.
The NIPPON DATA 90 project collected 8,383 community residents in 300 randomly selected areas as baseline data in 1990, administered four follow-up QoL surveys, and evaluated mortality statistics. We conducted multinomial logistic regression analysis to compare past smokers and current smokers to never smokers, with impaired QoL and mortality as outcomes.
In four follow-ups, QoL data was collected from 2,035, 2,252, 2,522, and 3,280 participants in 1995, 2000, 2005, and 2012, respectively. In the 1995 follow-up, current smoking at baseline was not associated with worse QoL. In 2000 and 2005 follow-ups, smoking was significantly associated with worse QoL (odds ratio [OR] 2.1; 95% confidence interval [CI], 1.33-3.36 and OR 2.29; 95% CI, 1.38-3.80, respectively). In the 2012 follow-up, smoking was not associated with QoL. Sensitivity analysis did not change the result significantly.
In this study we found that baseline smoking was associated with worse QoL in long-follow-up.
吸烟是否与生活质量（QoL）下降有关存在争议。本研究旨在通过一项长期队列研究来探讨吸烟与主观 QoL 之间的关系。
NIPPON DATA 90 项目于 1990 年在 300 个随机选定的地区收集了 8383 名社区居民的基线数据，进行了四次随访 QoL 调查，并评估了死亡率统计数据。我们采用多项逻辑回归分析比较了过去吸烟者和当前吸烟者与从不吸烟者的关系，将生活质量受损和死亡作为结局。
在四次随访中，1995 年、2000 年、2005 年和 2012 年分别从 2035、2252、2522 和 3280 名参与者中收集了 QoL 数据。在 1995 年的随访中，基线时的当前吸烟与较差的 QoL 无关。在 2000 年和 2005 年的随访中，吸烟与较差的 QoL 显著相关（比值比 [OR] 2.1；95%置信区间 [CI] 1.33-3.36 和 OR 2.29；95%CI 1.38-3.80）。在 2012 年的随访中，吸烟与 QoL 无关。敏感性分析并未显著改变结果。
在这项研究中，我们发现基线吸烟与长期随访中的较差 QoL 相关。
