Simon Sharon Sanz, Brucki Sonia Maria Dozzi, Fonseca Luciana Mascarenhas, Becker Jacqueline, Cappi Carolina, Marques Andrea Horvath, Heyn Patricia C, Gonçalves Priscila Dib, Martins Silvia S, Busatto Geraldo, Bertola Laiss, Suemoto Claudia Kimie, Nitrini Ricardo, Caramelli Paulo, Yassuda Monica Sanches, Miotto Eliane Correa, Grinberg Lea Tenenholz, Arce Renteria Miguel, Alegria Margarita, Stern Yaakov, Rivera-Mindt Monica
Cognitive Neuroscience Division Department of Neurology Columbia University Vagelos College of Physicians and Surgeons New York New York USA.
Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology Columbia University Vagelos College of Physicians and Surgeons New York New York USA.
Alzheimers Dement (N Y). 2023 Sep 23;9(3):e12425. doi: 10.1002/trc2.12425. eCollection 2023 Jul-Sep.
The Brazilian population in the United States (U.S.), a Latinx subgroup, is rapidly growing and aging but remains underrepresented in U.S. health research. In addition to group-specific genetic and environmental risks, Brazilian immigrants and their offspring in the U.S. likely have cumulative risks for health inequities.It is estimated that 71% of Brazilian immigrants in the U.S. are undocumented, which may limit healthcare access/utilization. Furthermore, mental health is reported as a health priority by Brazilian immigrants in the U.S., and there is a lack of research on Alzheimer's disease and related dementia (AD/ADRD) in this population.
We reviewed the scientific literature using traditional (e.g., PubMed) sources and databases generated by U.S. and Brazilian governments, as well as international organizations, and press articles.
This perspective review lists recommendations for researchers, health providers, and policymakers to promote greater inclusion of U.S. Brazilian populations in health research and care. The review identifies research areas in need of attention to address health inequities and promote mental/brain health in Brazilian immigrants and their offspring living in the U.S. These research areas are: 1) epidemiological studies to map the prevalence and incidence of mental/brain health conditions; 2) research on aging and AD/ADRD risk factors among Brazilian populations in the U.S.; and 3) the need for greater representation of U.S-residing Brazilian population in other relevant research areas involving genetics, neuropathology, and clinical trials.
The recommendation and research efforts proposed should help to pave the way for the development of community-engagement research and to promote mental/brain health education, improvement of mental/brain health and AD/ADRD services, and the development of culturally-informed intervention to the U.S.-residing Brazilian communities.
The Brazilian population in the United States is growing but is underrepresented in U.S. health research.Approximately 71% of Brazilian immigrants in the United States are undocumented, with an increased risk for health inequities.Mental health is reported as a central health priority by Brazilian immigrants in the United States.There is a lack of research on Alzheimer's disease and other dementias (ADRD) in Brazilian immigrants in the United States.Epidemiological research is needed to map the prevalence/incidence of mental health conditions and ADRD risk factors among Brazilian immigrants in the United States.
在美国的巴西人群体是拉丁裔亚群体，其数量正在迅速增长且人口老龄化，但在美国健康研究中的代表性仍然不足。除了特定群体的遗传和环境风险外，在美国的巴西移民及其后代可能还面临着健康不平等的累积风险。据估计，在美国的巴西移民中有71%是无证移民，这可能会限制他们获得医疗保健服务的机会和利用率。此外，心理健康被报告为在美国的巴西移民的一项健康优先事项，而针对该群体的阿尔茨海默病及相关痴呆症（AD/ADRD）的研究却很匮乏。
我们使用传统来源（如PubMed）以及美国和巴西政府、国际组织生成的数据库和新闻文章对科学文献进行了综述。
这篇观点性综述列出了对研究人员、医疗服务提供者和政策制定者的建议，以促进美国巴西人群体更多地参与健康研究和护理。该综述确定了需要关注的研究领域，以解决健康不平等问题，并促进生活在美国的巴西移民及其后代的心理健康/大脑健康。这些研究领域包括：1）开展流行病学研究，以摸清心理健康/大脑健康状况的患病率和发病率；2）研究美国巴西人群体中的衰老以及AD/ADRD风险因素；3）需要让居住在美国的巴西人群体在涉及遗传学、神经病理学和临床试验的其他相关研究领域中得到更多体现。
所提出的建议和研究工作应有助于为社区参与研究的发展铺平道路，并促进心理健康/大脑健康教育、改善心理健康/大脑健康及AD/ADRD服务，以及为居住在美国的巴西社区制定具有文化针对性的干预措施。
在美国的巴西人群体正在增长，但在美国健康研究中的代表性不足。在美国的巴西移民中约71%是无证移民，健康不平等风险增加。心理健康被报告为在美国的巴西移民的一项核心健康优先事项。在美国的巴西移民中缺乏对阿尔茨海默病和其他痴呆症（ADRD）的研究。需要开展流行病学研究，以摸清美国巴西移民中心理健康状况和ADRD风险因素的患病率/发病率。
